The authors of this paper do not have any commercial associations that might pose a conflict of interest in connection with this manuscript.
Bipolar affective disorder in a male with a deletion of Y chromosome – a case report
Article first published online: 17 MAY 2005
Volume 7, Issue 3, pages 298–301, June 2005
How to Cite
Olajossy, M., Olajossy-Hilkesberger, L. and Tkaczuk-Włach, J. (2005), Bipolar affective disorder in a male with a deletion of Y chromosome – a case report. Bipolar Disorders, 7: 298–301. doi: 10.1111/j.1399-5618.2005.00198.x
- Issue published online: 17 MAY 2005
- Article first published online: 17 MAY 2005
- Received 2 December 2003, revised and accepted for publication 28 September 2004
- bipolar disorder;
- chromosomal abnormality;
- chromosome Y;
We report on a 25-year-old male with bipolar disorder, dysmorphic features and a deletion of the long arm of Y chromosome. A potential association between sex chromosome abnormalities and a susceptibility to major psychiatric disorders has been documented. However there have been very few reports on the coincidence of Y chromosome aberrations with bipolar disorder. Cytogenetic studies have contributed to the identification of several disease genes. Karyotyping of patients with bipolar disorder in order to identify candidate regions for linkage studies has been recommended.