Stability of estimated IQ across mood state in patients with bipolar disorder


  • None of the authors have any commercial associations that pose a conflict of interest in connection with this manuscript.

Paula K Shear, PhD, Department of Psychology, University of Cincinnati, PO Box 210376, Cincinnati, OH 45221-0376, USA. Fax: (513) 556 1904; e-mail:


Objectives:  The goal of this study was to assess the impact of mania symptoms on the stability of the American version of the National Adult Reading Test (ANART), a measure that provides a putative estimate of premorbid intellectual functioning.

Methods:  The ANART was administered to a sample of 10 inpatients with bipolar disorder who were experiencing an acute episode of mania. During a subsequent follow-up visit during which these individuals exhibited at most minimal mood symptoms, the ANART was re-administered.

Results:  ANART estimated intelligence quotient (IQ) scores during mania and affective stability were assessed in the 10 patients using a paired sample t-test. Within-subject performance across the two mood states did not significantly differ [t(9) = −1.24, p = 0.25]. Additionally, the greatest individual difference across mood states was only 3.68 points, and the average estimated IQ difference across mood states was 1.66.

Conclusions:  While the results are preliminary and based on a small sample, the highly consistent scores achieved across mood states in this study suggest that the ANART is a reliable indicator of premorbid IQ.