The authors of this paper do not have any commercial associations that might pose a conflict of interest in connection with this manuscript.
Correlates of suicide attempt history in bipolar disorder: a stress-diathesis perspective
Article first published online: 17 OCT 2006
Volume 8, Issue 5p2, pages 551–557, October 2006
How to Cite
Grunebaum, M. F., Ramsay, S. R., Galfalvy, H. C., Ellis, S. P., Burke, A. K., Sher, L., Printz, D. J., Kahn, D. A., John Mann, J. and Oquendo, M. A. (2006), Correlates of suicide attempt history in bipolar disorder: a stress-diathesis perspective. Bipolar Disorders, 8: 551–557. doi: 10.1111/j.1399-5618.2006.00304.x
- Issue published online: 17 OCT 2006
- Article first published online: 17 OCT 2006
- Received 4 January 2005, revised and accepted for publication 12 December 2005
- bipolar disorder;
- suicide attempt
Objectives: Distinguishing clinical characteristics of bipolar patients who have made a suicide attempt may help to identify at-risk individuals. We sought to identify such factors and to consider them within a stress-diathesis model of suicidal behavior.
Methods: Patients with bipolar disorder (N = 96) were compared with respect to the presence or absence at baseline evaluation of a history of suicide attempt. We used multiple logistic regression analysis to assess the unique associations of independent variables to history of a past suicide attempt.
Results: The regression analysis showed that a history of suicide attempt in bipolar disorder was associated with greater recent suicidal ideation, more psychiatric hospitalizations, lifetime aggressive traits and an earlier age at onset of a first mood episode.
Conclusions: Aggressive traits and early treatment of mood disorders, especially major depressive episodes, are potential targets for suicide prevention in bipolar disorder.