The authors of this paper do not have any commercial associations that might pose a conflict of interest in connection with this manuscript.
Electroconvulsive therapy: an effective therapy of medication-resistant bipolar disorder
Article first published online: 12 MAY 2006
Volume 8, Issue 3, pages 304–306, June 2006
How to Cite
Sienaert, P. and Peuskens, J. (2006), Electroconvulsive therapy: an effective therapy of medication-resistant bipolar disorder. Bipolar Disorders, 8: 304–306. doi: 10.1111/j.1399-5618.2006.00317.x
- Issue published online: 12 MAY 2006
- Article first published online: 12 MAY 2006
- Received 7 May 2005, revised and accepted for publication 13 January 2006
- bipolar disorder;
- continuation ECT;
- electroconvulsive therapy;
- mixed state;
Objectives: We report our experience with a medication-refractory patient with bipolar I disorder, who remained clinically stable under continuation electroconvulsive therapy (C-ECT). We found ECT to be effective in providing functionality for a patient when various medications had failed.
Methods and results: A 53-year-old woman with a 31-year history of recurrent manic and depressive episodes poorly responsive to medications warranted an ECT trial. Remission was achieved after 12 treatments and C-ECT at weekly intervals was used as maintenance therapy. C-ECT was continued for 37 months and 85 treatments, and discontinued when anesthetic difficulties precluded further treatment. Three months after the last ECT, she was readmitted in a severe manic relapse. Restarting ECT caused rapid remission. There are no signs of cognitive deterioration during C-ECT.
Conclusion: Long-term C-ECT is an effective and safe prophylactic treatment in individual treatment-resistant patients with bipolar disorder.