• 1
    Kraepelin E. Manic-Depressive Insanity. New York: Arno Press, 1976 (translated by Barclay RM, edited by Robertson GM; originally published in 1921).
  • 2
    Zarate CA Jr, Tohen M, Land M, Cavanagh S. Functional impairment and cognition in bipolar disorder. Psychiatr Q 2000; 71: 309329.
  • 3
    Rennie TAC. Long-term outcome of major psychoses. Am J Psychiatry 1942; 98: 801814.
  • 4
    Tsuang MT, Dempsey GM. Long-term outcome of major psychoses. II. Schizoaffective disorder compared with schizophrenia, affective disorders, and a surgical control group. Arch Gen Psychiatry 1979; 36: 13021304.
  • 5
    Tohen M, Waternaux CM, Tsuang MT. Outcome in mania. A 4-year prospective follow-up of 75 patients utilizing survival analysis. Arch Gen Psychiatry 1990; 47: 11061111.
  • 6
    Tohen M, Hennen J, Zarate CM Jr et al. Two-year syndromal and functional recovery in 219 cases of first-episode major affective disorder with psychotic features. Am J Psychiatry 2000; 157: 220228.
  • 7
    Carlson GA, Kotin J, Davenport YB, Adland M. Follow-up of 53 bipolar manic-depressive patients. Br J Psychiatry 1974; 124: 134139.
  • 8
    Goldberg JF, Harrow M, Grossman LS. Course and outcome in bipolar affective disorder: a longitudinal follow-up study. Am J Psychiatry 1995; 152: 379384.
  • 9
    Strakowski SM, Keck PE Jr, McElroy SL et al. Twelve-month outcome after a first hospitalization for affective psychosis. Arch Gen Psychiatry 1998; 55: 4955.
  • 10
    Keck PE Jr, McElroy SL, Strakowski SM et al. 12-month outcome of patients with bipolar disorder following hospitalization for a manic or mixed episode. Am J Psychiatry 1998; 155: 646652.
  • 11
    Dean BB, Gerner D, Gerner RH. A systematic review evaluating health-related quality of life, work impairment, and healthcare costs and utilization in bipolar disorder. Curr Med Res Opin 2004; 20: 139154.
  • 12
    Tohen M, Greenfield SF, Weiss RD, Zarate CA Jr, Vagge LM. The effect of comorbid substance use disorders on the course of bipolar disorder: a review. Harv Rev Psychiatry 1998; 6: 133141.
  • 13
    Cannon M, Jones P, Gilvarry C et al. Premorbid social functioning in schizophrenia and bipolar disorder: similarities and differences. Am J Psychiatry 1997; 154: 15441550.
  • 14
    Gitlin MJ, Swendsen J, Heller TL, Hammen C. Relapse and impairment in bipolar disorder. Am J Psychiatry 1995; 152: 16351640.
  • 15
    Martinez-Aran A, Vieta E, Reinares M et al. Cognitive function across manic or hypomanic, depressed, and euthymic states in bipolar disorder. Am J Psychiatry 2004; 161: 262270.
  • 16
    Martinez-Aran A, Vieta E, Colom F et al. Cognitive impairment in euthymic bipolar patients: implications for clinical and functional outcome. Bipolar Disord 2004; 6: 224232.
  • 17
    Marangell LB. The importance of subsyndromal symptoms in bipolar disorder. J Clin Psychiatry 2004; 65 (Suppl. 10): 2427.
  • 18
    MacQueen GM, Young LT, Robb JC, Marriott M, Cooke RG, Joffe RT. Effect of number of episodes on wellbeing and functioning of patients with bipolar disorder. Acta Psychiatr Scand 2000; 101: 374381.
  • 19
    Dion GL, Tohen M, Anthony WA, Waternaux CS. Symptoms and functioning of patients with bipolar disorder six months after hospitalization. Hosp Community Psychiatry 1988; 39: 652657.
  • 20
    O'Connell RA, Mayo JA, Flatow L, Cuthbertson B, O'Brien BE. Outcome of bipolar disorder on long-term treatment with lithium. Br J Psychiatry 1991; 159: 123129.
  • 21
    Atre-Vaidya N, Taylor MA, Seidenberg M, Reed R, Perrine A, Glick-Oberwise F. Cognitive deficits, psychopathology, and psychosocial functioning in bipolar mood disorder. Neuropsychiatry Neuropsychol Behav Neurol 1998; 11: 120126.
  • 22
    Zubieta JK, Huguelet P, O'Neil RL, Giordani BJ. Cognitive function in euthymic bipolar I disorder. Psychiatry Res 2001; 102: 920.
  • 23
    Dickerson FB, Sommerville J, Origoni AE, Ringel NB, Parente F. Outpatients with schizophrenia and bipolar I disorder: do they differ in their cognitive and social functioning? Psychiatry Res 2001; 102: 2127.
  • 24
    Martinez-Aran A, Vieta E, Colom F et al. Neuropsychological performance in depressed and euthymic bipolar patients. Neuropsychobiology 2002; 46 (Suppl. 1): 1621.
  • 25
    Goldberg TE, Gold JM, Greenberg R et al. Contrasts between patients with affective disorders and patients with schizophrenia on a neuropsychological test battery. Am J Psychiatry 1993; 150: 13551362.
  • 26
    Hamilton M. A rating scale for depression. J Neurol Neurosurg Psychiatry 1960; 23: 5662.
  • 27
    Ramos-Brieva JA, Cordero-Villafafila A. A new validation of the Hamilton rating scale for depression. J Psychiatr Res 1988; 22: 2128.
  • 28
    Young RC, Biggs JT, Ziegler VE, Meyer DA. A rating scale for mania: reliability, validity and sensitivity. Br J Psychiatry 1978; 133: 429435.
  • 29
    Colom F, Vieta E, Martinez-Aran A et al. Spanish version of a scale for the assessment of mania: validity and reliability of the Young Mania Rating Scale. Med Clin (Barc) 2002; 119: 366371.
  • 30
    Altshuler LL, Gitlin MJ, Mintz J, Leight KL, Frye MA. Subsyndromal depression is associated with functional impairment in patients with bipolar disorder. J Clin Psychiatry 2002; 63: 807811.
  • 31
    Liberman RP, Kopelowicz A. Recovery from schizophrenia: a concept in search of research. Psychiatr Serv 2005; 56: 735742.
  • 32
    Kessler RC, Barker PR, Colpe LJ et al. Screening for serious mental illness in the general population. Arch Gen Psychiatry 2003; 60: 184189.
  • 33
    Whitehorn D, Kopala LC. Neuromotor dysfunction in early psychosis. Ann Clin Psychiatry 2002; 14: 113121.
  • 34
    Lezak MD. Neuropsychological Assessment, 3rd edn. New York: Oxford University Press, 1995.
  • 35
    Spreen O, Strauss E. A Compendium of Neuropsychological Tests. Administration, Norms Commentary, 2nd edn. New York: Oxford University Press, 1998.
  • 36
    Weschler D. Weschler Adult Intelligence Scale. Cleveland, OH: The Psychological Corporation, 1955.
  • 37
    Heaton RK. Wisconsin Card Sorting Test Manual. Odessa, FL: Psychological Assessment Resources, 1981.
  • 38
    Golden CJ. Stroop Colour and Word Test. Chicago: Stoelting, 1978.
  • 39
    Benton AL, Hamsher K. Multilingual Aphasia Examination. Iowa City: University of Iowa, 1976.
  • 40
    Reitan RM. Validity of the Trail Making Test as a indication of organic brain damage. Percept Mot Skills 1958; 8: 271276.
  • 41
    Delis DC, Kramer JH, Kaplan E, Ober B. California Verbal Learning Test. New York: Psychological Corporation, 1987.
  • 42
    Cohen J. Statistical Power Analysis for the Behavioural Science, 2nd edn. Hillsdale, NJ: Lawrence Erlbaum Associates, 1988.
  • 43
    Martinez-Aran A, Penades R, Vieta E et al. Executive function in patients with remitted bipolar disorder and schizophrenia and its relationship with functional outcome. Psychother Psychosom 2002; 71: 3946.
  • 44
    Altshuler LL, Ventura J, Van Gorp WG, Green MF, Theberge DC, Mintz J. Neurocognitive function in clinically stable men with bipolar I disorder or schizophrenia and normal control subjects. Biol Psychiatry 2004; 56: 560569.
  • 45
    Dixon T, Kravariti E, Frith C, Murray RM, McGuire PK. Effect of symptoms on executive function in bipolar illness. Psychol Med 2004; 34: 811821.
  • 46
    Malhi GS, Ivanovski B, Szekeres V, Olley A. Bipolar disorder: it's all in your mind? The neuropsychological profile of a biological disorder. Can J Psychiatry 2004; 49: 813819.
  • 47
    Balanza-Martinez V, Tabares-Seisdedos R, Selva-Vera G et al. Persistent cognitive dysfunctions in bipolar I disorder and schizophrenic patients: a 3-year follow-up study. Psychother Psychosom 2005; 74: 113119.
  • 48
    Glahn DC, Bearden CE, Niendam TA, Escamilla MA. The feasibility of neuropsychological endophenotypes in the search for genes associated with bipolar affective disorder. Bipolar Disord 2004; 6: 171182.
  • 49
    Keri S, Kelemen O, Benedek G, Janka Z. Different trait markers for schizophrenia and bipolar disorder: a neurocognitive approach. Psychol Med 2001; 31: 915922.
  • 50
    Ferrier IN, Stanton BR, Kelly TP, Scott J. Neuropsychological function in euthymic patients with bipolar disorder. Br J Psychiatry 1999; 175: 246251.
  • 51
    Coryell W, Turvey C, Endicott J et al. Bipolar I affective disorder: predictors of outcome after 15 years. J Affect Disord 1998; 50: 109116.
  • 52
    MacQueen GM, Young LT, Joffe RT. A review of psychosocial outcome in patients with bipolar disorder. Acta Psychiatr Scand 2001; 103: 163170.
  • 53
    MacQueen GM, Young LT, Robb JC, Cooke RG, Joffe RT. Levels of functioning and well-being in recovered psychotic versus nonpsychotic mania. J Affect Disord 1997; 46: 6972.
  • 54
    Harrow M, Goldberg JF, Grossman LS, Meltzer HY. Outcome in manic disorders. A naturalistic follow-up study. Arch Gen Psychiatry 1990; 47: 665671.
  • 55
    Martinez-Aran A, Vieta E, Colom F et al. Do cognitive complaints in euthymic bipolar patients reflect objective cognitive impairment? Psychother Psychosom 2005; 74: 295302.
  • 56
    Goldberg JF, Harrow M, Leon AC. Lithium treatment of bipolar affective disorders under naturalistic followup conditions. Psychopharmacol Bull 1996; 32: 4754.
  • 57
    World Health Organization. The World Health Report 2001; Mental Health: New Understanding, New Hope. Geneva: WHO ed., 2001.
  • 58
    Chisholm D, Sanderson K, Ayuso-Mateos JL, Saxena S. Reducing the global burden of depression: population-level analysis of intervention cost-effectiveness in 14 world regions. Br J Psychiatry 2004; 184: 393403.
  • 59
    Vieta E, Colom F. Psychological interventions in bipolar disorder: from wishful thinking to an evidence-based approach. Acta Psychiatr Scand Suppl 2004; 3438.