The authors of this paper do not have any commercial associations that might pose a conflict of interest in connection with this manuscript.
Context processing performance in bipolar disorder patients
Article first published online: 5 APR 2007
Volume 9, Issue 3, pages 230–237, May 2007
How to Cite
Brambilla, P., MacDonald, A. W., Sassi, R. B., Johnson, M. K., Mallinger, A. G., Carter, C. S. and Soares, J. C. (2007), Context processing performance in bipolar disorder patients. Bipolar Disorders, 9: 230–237. doi: 10.1111/j.1399-5618.2007.00398.x
- Issue published online: 5 APR 2007
- Article first published online: 5 APR 2007
- Received 21 January 2005, revised and accepted for publication 31 May 2006
- continuous performance test (CPT);
- executive functions;
- mood disorders;
- working memory
Objectives: Context processing is the adaptive control of current behavior through the use of prior context information. It has been found to be impaired in schizophrenia. Some studies have indicated that, compared with patients with schizophrenia, those with bipolar disorder (BPD) display a similar but less severe neuropsychological pattern of impairment. However, this cognitive dimension has not yet been examined in BPD patients in the existing literature.
Methods: An expectancy version of the AX continuous performance test (AX-CPT) was administered to 15 bipolar outpatients and 26 healthy controls. Patients with schizophrenia, in which context processing deficits are known to occur, were used as a reference group.
Results: Bipolar patients showed a context processing deficit relative to healthy controls, although this was less severe and generalized than in schizophrenia patients.
Conclusions: These findings suggest there are milder impairments in context processing in BPD compared with schizophrenia. However, the severity of possible context processing deficits in BPD may have been underestimated in our sample of mostly euthymic outpatients.