JB receives or has received research support from, is or has been a speaker for, or is or has been on the advisory board for Shire, Eli Lilly & Co., Pfizer, McNeil, Abbott, Bristol-Myers Squibb, New River Pharmaceuticals, Cephalon, Janssen, Novartis, UCB Pharma, AstraZeneca, Forest Laboratories, GlaxoSmithKline, Neurosearch, Stanley Medical Institute, Inc., Lilly Foundation, Prechter Foundation, NIMH, NICHD, and NIDA. TEW receives grant support from, is a speaker for, or is a consultant for Abbott, McNeil, Eli Lilly & Co., NIDA, Merck, Shire, Novartis, and Cephalon. TS receives or has received research support from, is or has been a speaker for, or is or has been on the advisory board for Shire Laboratories, Inc., Eli Lilly & Co., GlaxoSmithKline, Pfizer, McNeil, Wyeth Ayerst, Novartis, and NIMH. SVF receives or has received research support from, is or has been a speaker for, or is or has been on the advisory board for Eli Lilly & Co., McNeil Consumer & Specialty Pharmaceuticals, Shire US, Inc., Noven Pharmaceuticals, Cephalon, NIMH, NICHHD, and NINDS. EM receives or has received grant support from McNeil Pediatrics and Janssen. JW receives or has received research support from, is or has been a speaker for, or is or has been on the advisory board for Pfizer, Shire, Eli Lilly & Co., NIMH, and Janssen. CRP, AH, MCM, DK, and TM do not have any financial interests to disclose.
Examination of concordance between maternal and youth reports in the diagnosis of pediatric bipolar disorder
Article first published online: 14 APR 2009
© 2009 The Authors. Journal compilation © 2009 Blackwell Munksgaard
Volume 11, Issue 3, pages 298–306, May 2009
How to Cite
Biederman, J., Petty, C. R., Wilens, T. E., Spencer, T., Henin, A., Faraone, S. V., Mick, E., Monuteaux, M. C., Kenealy, D., Mirto, T. and Wozniak, J. (2009), Examination of concordance between maternal and youth reports in the diagnosis of pediatric bipolar disorder. Bipolar Disorders, 11: 298–306. doi: 10.1111/j.1399-5618.2009.00671.x
- Issue published online: 14 APR 2009
- Article first published online: 14 APR 2009
- Received 4 April 2008, revised and accepted for publication 13 August 2008
- maternal report;
- pediatric bipolar disorder
Objective: While concordance between mother and child report continues to be the gold standard in the assessment of pediatric bipolar disorder, uncertainty develops when a mother’s report is not endorsed by the youth. To this end we compared discordant (mother positive and youth negative) and concordant (mother and youth positive) cases.
Methods: Subjects were 98 adolescents (12–19 years of age) derived from family studies of bipolar disorder in youth who had both self-reported and mother-reported assessments. Comparisons were made between discordant (n = 35) and concordant (n = 59) cases on a wide range of clinical correlates.
Results: Mothers in both groups reported similar rates of symptoms of mania and depression. Within the concordant group, mothers and youth reported similar rates of symptoms of mania. There were no differences between the concordant and discordant groups in onset, duration, or impairment of mania, rates of psychiatric hospitalization, cognitive variables, or rates of disorders in family members.
Conclusions: The similarities between discordant and concordant reports in symptomatology of mania and depression, rates of comorbidities, treatment needs, and other clinical correlates suggest that a mother-based diagnosis of mania should not be discounted in discrepant cases in which the youth fails to endorse the diagnosis.