PDH has received grant support from AstraZeneca, and in the past year, he has served as a consultant for Eli Lilly & Co., Johnson & Johnson, Merck & Co., Shire Pharma, and Dainippon Sumitomo America. BTM, AEP, CAD, PSW, MHT, JRL, JAM, CB and TLP have no conflicts of interest to report.
Relationship of the Brief UCSD Performance-based Skills Assessment (UPSA-B) to multiple indicators of functioning in people with schizophrenia and bipolar disorder
Article first published online: 24 JAN 2010
© 2010 The Authors. Journal compilation © 2010 John Wiley & Sons A/S
Volume 12, Issue 1, pages 45–55, February 2010
How to Cite
Mausbach, B. T., Harvey, P. D., Pulver, A. E., Depp, C. A., Wolyniec, P. S., Thornquist, M. H., Luke, J. R., McGrath, J. A., Bowie, C. R. and Patterson, T. L. (2010), Relationship of the Brief UCSD Performance-based Skills Assessment (UPSA-B) to multiple indicators of functioning in people with schizophrenia and bipolar disorder. Bipolar Disorders, 12: 45–55. doi: 10.1111/j.1399-5618.2009.00787.x
- Issue published online: 24 JAN 2010
- Article first published online: 24 JAN 2010
- Received 16 March 2009, revised and accepted for publication 6 October 2009
- functional capacity;
- functional outcome;
- severe mental illness
Mausbach BT, Harvey PD, Pulver AE, Depp CA, Wolyniec PS, Thornquist MH, Luke JR, McGrath JA, Bowie CR, Patterson TL. Relationship of the Brief UCSD Performance-based Skills Assessment (UPSA-B) to multiple indicators of functioning in people with schizophrenia and bipolar disorder. Bipolar Disord 2010: 12: 45–55. © 2010 The Authors. Journal compilation © 2010 John Wiley & Sons A/S.
Objective: This study assessed the relationship between multiple indicators of ‘real-world’ functioning and scores on a brief performance-based measure of functional capacity known as the Brief University of California San Diego (UCSD) Performance-based Skills Assessment (UPSA-B) in a sample of 205 patients with either serious bipolar disorder (n = 89) or schizophrenia (n = 116).
Methods: Participants were administered the UPSA-B and assessed on the following functional domains: (i) independent living status (e.g., residing independently as head of household, living in residential care facility); (ii) informant reports of functioning (e.g., work skills, daily living skills); (iii) educational attainment and estimated premorbid IQ as measured by years of education and Wide Range Achievement Test reading scores, respectively; and (iv) employment.
Results: Better scores on the UPSA-B were associated with greater residential independence after controlling for age, diagnosis, and symptoms of psychopathology. Among both bipolar disorder and schizophrenia patients, higher UPSA-B scores were significantly related to better informant reports of functioning in daily living skills and work skills domains. Greater estimated premorbid IQ was associated with higher scores on the UPSA-B for both schizophrenia and bipolar disorder participants. Participants who were employed scored higher on the UPSA-B when controlling for age and diagnosis, but not when controlling for symptoms of psychopathology.
Conclusions: These data suggest the UPSA-B may be useful for assessing capacity for functioning in a number of domains in both people diagnosed with schizophrenia and bipolar disorder.