Improved survival after an out-of-hospital cardiac arrest using new guidelines


  • The data have been presented in part at the 29th Congress of the Scandinavian Society of Anaesthesiology and Intensive Care Medicine in Göteborg, Sweden, 5–8 September 2007.

Jacob Steinmetz
Department of Anaesthesia, HOC 4231
Copenhagen University Hospital, Rigshospitalet
DK-2100 Copenhagen


Background: An out-of-hospital cardiac arrest (OHCA) is associated with a poor prognosis. We hypothesized that the implementations of 2005 European Resuscitation Council resuscitation guidelines were associated with improved 30-day survival after OHCA.

Methods: We prospectively recorded data on all patients with OHCA treated by the Mobile Emergency Care Unit of Copenhagen in two periods: 1 June 2004 until 31 August 2005 (before implementation) and 1 January 2006 until 31 March 2007 (after implementation), separated by a 4-month period in which the above-mentioned change took place.

Results: We found that 30-day survival increased after the implementation from 31/372 (8.3%) to 67/419 (16%), P=0.001. ROSC at hospital admission, as well as survival to hospital discharge, were obtained in a significantly higher proportion from 23.4% to 39.1%, P<0.0001, and from 7.9% to 16.3%, P=0.0004, respectively. Treatment after implementation was confirmed as a significant predictor of better 30-day survival in a logistic regression analysis.

Conclusion: The implementation of new resuscitation guidelines was associated with improved 30-day survival after OHCA.