Intravenous Immune Serum Globulin in Immune Thrombocytopenia: Clinical Results and Biochemical Evaluation


Department of Pediatrics, The New York Hospital, Cornell Medical Center, 525 East 68th Street, New York, NY 10021 (USA)


Intravenous gamma-globulin of the pH 4-treated Swiss Red Cross (SRC) preparation is an effective therapy for acute and chronic immune thrombocytopenia (ITP) of childhood and chronic ITP in adults. Patients who may respond satisfactorily to treatment include those without detectable immune complexes and those with poor response to pre-treatment. Results are especially good in children, half of whom with chronic conditions are able to discontinue therapy.