Effectiveness of High-Dose Intravenous Gamma Globulin Therapy in Acquired von Willebrand's Disease

Authors


Department of Haematology, University Hospital Dijkzigt Dr. Molewaterplein 40 NL-3015 GD Rotterdam (The Netherlands)

Abstract

An 82-year-old patient with acquired von Willebrand's disease in association with a non-Hodgkin lymphoma and a benign IgGλ monoclonal paraproteinaemia is described with severe recurring nasopharyngeal bleedings, who responded poorly to desmopressin (DDAVP) and factor VIII/von Willebrand factor concentrates but was successfully treated with high-dose intravenous γ-globulin therapy.

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