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Abstract

  1. Top of page
  2. Abstract
  3. REFERENCES

The amino acid sequence of a brain-specific protein, S-100, has been determined by the analysis of four cyanogen bromide peptides and fourteen tryptic peptides derived from the protein. The protein chain consists of 91 amino acid residues and has a molecular weight of 10 507. The sequence shows regions of strong clustering of hydrophobic, basic and acidic amino acids, with an apparent calcium-binding site in the acidic cluster.

Abbreviations
Tos-Phe-CH2Cl

l-1-tosylamido-2-phenylethyl chloromethyl ketone

Pth

phenylthiohydantoin

Enzymes
 

Trypsin (EC 3.4.21.4)

 

carboxypeptidase A (EC 3.4.12.2)

 

carboxypeptidase B (EC 3.4.12.3)

 

carboxypeptidase P (EC 3.4.12.-)

REFERENCES

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  2. Abstract
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