The Seminal Vesicle of the Bull:

A New and Very Rich Source of Nerve Growth Factor

Authors

  • Hans-Dieter HOFMANN,

    1. Institut für Anatomie und Zellbiologie der Philipps-Universität Marburg, Robert-Koch-Straße 6, D-3550 Marburg, Federal Republic of Germany
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  • Klaus UNSICKER

    1. Institut für Anatomie und Zellbiologie der Philipps-Universität Marburg, Robert-Koch-Straße 6, D-3550 Marburg, Federal Republic of Germany
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  • Note Added in Proof. The apparent molecular weight of NGF from bovine seminal plasma determined by SDS gel electrophoresis and the transblot technique is identical to that of NGF from bovine seminal vesicle and mouse submaxillary gland.

Abstract

Evidence is presented that the seminal vesicle of the bull is an important source of a protein which is very similar to nerve growth factor from mouse submaxillary gland. Its chemical and biological properties in vitro are compared with those of nerve growth factor from other sources.

Abbreviations
NGF

nerve growth factor

SVE

seminal vesicle extract

TosArgOMe

Nα-p-tocenesulphonyl-l-arginine methyl ester

BzArgOEt

Nα-benzoyl-l-arginine ethyl ester

BzArgNap

Nα-benzoyl-l-arginine p-nitroanilide

SDS

sodium dodecyl sulphate

Ancillary