Complete amino acid sequence of a basic 21-kDa protein from bovine brain cytosol


Correspondence to P. Jollès, Laboratoire des Protéines, Université de Paris V, 45, rue des Saints-Pères, F-75270 Paris Cédex 06, France


The complete amino acid sequence (186 amino acid residues) of a basic cytosolic protein from bovine brain has been determined. It was previously described as a phosphatidylethanolamine binding protein. Computer analyses have been used to calculate its hydropathy profile and to predict its secondary structure. Comparison with other proteins did not detect any significant sequence similarity, except for a short region which presents 53% sequence homology with bovine phosphatidylcholine transfer protein.