Protein interaction with ice

Authors


Correspondence to C. L. Hew, Department of Clinical Biochemistry, University of Toronto, 100 College Street, Toronto, Ontario M5G 1L5, Canada

Abstract

Many organisms have evolved novel mechanisms to minimize freezing injury due to extracellular ice formation. This article reviews our present knowledge on the structure and mode of action of two types of proteins capable of ice interaction. The antifreeze proteins inhibit ice crystal formation and alter ice growth habits. The ice nucleation proteins, on the other hand, provide a proper template to stimulate ice growth. The potential applications of these proteins in different industries are discussed.

Abbreviations
INA

ice nucleation activators

INP

ice nucleation proteins

AFP

antifreeze proteins or polypeptides

AFGP

antifreeze glycoproteins

f

cumulative ice nucleation frequency

z

number of cells