Does concommitant splenectomy raise the mortality of liver transplant recipients?
Article first published online: 2 JUN 2008
Volume 7, Issue Supplement S1, pages 634–636, December 1994
How to Cite
Lüsebrink, R., Blumhardt, G., Lohmann, R., Bachmann, S., Knoop, M., Lemmens, H.P. and Neuhaus, P. (1994), Does concommitant splenectomy raise the mortality of liver transplant recipients?. Transplant International, 7: 634–636. doi: 10.1111/j.1432-2277.1994.tb01461.x
- Issue published online: 2 JUN 2008
- Article first published online: 2 JUN 2008
- Liver transplantation;
Abstract Within a 17-month period, 130 orthotopic liver transplantations were performed in our hospital. Nine of these were retransplantations and were not included in our analysis. In the remaining 121 patients, splenectomy was performed in 34 patients, either synchronously with the transplant procedure (27 patients) or in the postoperative period (7 patients). Indications for splenectomy were lienalis-teal syndrome in 15 patients and hypersplenism in 15 cases. The number of rejection episodes was fairly equal in both groups (splenectomized vs. non-plenectomized, 61.7% vs. 63.9%, respectively). There was a marked difference in the frequency of infectious episodes (61.7% vs. 25.3%) that resulted in a decreased survival rate (77.5% vs. 95.4%) for splenectomized patients. Therefore, we recommend splenectomy only for very selected patients and investigate the banding of the splenic artery as an alternative.