Influenza pneumonia in a paediatric lung transplant recipient

Authors

  • John L. Faul,

    1. Division of Pulmonary and Critical Care Medicine, Stanford University Medical Center, Stanford, CA 94305-5407, USA Fax: + 1–650-7 25–5489
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  • Olufemi A. Akindipe,

    1. Division of Pulmonary and Critical Care Medicine, Stanford University Medical Center, Stanford, CA 94305-5407, USA Fax: + 1–650-7 25–5489
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  • Gerald J. Berry,

    1. Department of Pathology, Stanford University Medical Center, Stanford, CA 94305, USA
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  • James Theodore

    Corresponding author
    1. Division of Pulmonary and Critical Care Medicine, Stanford University Medical Center, Stanford, CA 94305-5407, USA Fax: + 1–650-7 25–5489
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Division of Pulmonary and Critical Care Medicine, Stanford University Medical Center, Stanford, CA 94305-5407, USA Fax: + 1–650-7 25–5489

Abstract

Abstract Although a common cause of morbidity and mortality in the general population, influenza infections are uncommon in lung transplant recipients and, to date, have only been associated with transient declines in pulmonary function and a relatively benign clinical course. This paper describes severe influenza pneumonia in a 13-year-old paediatric lung transplant recipient (5 months after double lung transplantation). Influenza pneumonia was diagnosed by direct fluorescent antibody testing and viral culture of bronchoalveolar lavage fluid. The patient required mechanical ventilation for 2 days due to respiratory failure and fatigue. Since his recovery from this pneumonia, he has developed obliterative bronchiolitis and currently awaits re-transplantation.

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