A case of acute humoral rejection in liver transplantation: successful treatment with plasmapheresis and mycophenolate mofetil


A. Rostron, Liver Unit, Freeman Hospital, Newcastle upon Tyne, UK. Tel.: +44 191 244 8379; fax: +44 191 223 1152; e-mail: tonyrostron@doctors.org.uk


We present a case of a 23-year-old female who underwent orthotopic liver transplantation (OLTx) for biliary atresia, 22 years after a failed Kasai operation. Unusually, her postoperative course was complicated by severe acute humoral rejection. In this case report, we discuss her management as well as the role of plasmapheresis in treating allograft dysfunction secondary to acute humoral rejection in liver transplant patients.