Data presented at the 25th Annual Scientific Meeting, The American Society of Transplant Surgeons (ASTS) May 1999, Chicago, IL, USA and Fifth Congress of the International Liver Transplantation Society, August 26–28, 1999, Pittsburgh, PA, USA.
Thrombotic and nonthrombotic hepatic artery complications in adults and children following primary liver transplantation with long-term follow-up in 1000 consecutive patients*
Version of Record online: 22 NOV 2005
Volume 19, Issue 1, pages 27–37, January 2006
How to Cite
Jain, A., Costa, G., Marsh, W., Fontes, P., Devera, M., Mazariegos, G., Reyes, J., Patel, K., Mohanka, R., Gadomski, M., Fung, J. and Marcos, A. (2006), Thrombotic and nonthrombotic hepatic artery complications in adults and children following primary liver transplantation with long-term follow-up in 1000 consecutive patients. Transplant International, 19: 27–37. doi: 10.1111/j.1432-2277.2005.00224.x
- Issue online: 15 DEC 2005
- Version of Record online: 22 NOV 2005
- Received: 5 July 2005 Revision requested: 12 August 2005 Accepted: 6 September 2005
- early hepatic artery thrombosis;
- hepatic artery pseudo-aneurysm;
- hepatic artery stenosis;
- hepatic artery thrombosis;
- intermediate hepatic artery thrombosis;
- liver transplantation
Arterial complications have a major impact on survival after liver transplantation (LTx). The aim of this study was to examine arterial complications in adults and children after LTx. A total of 1000 consecutive primary LTx patients [mean age 40.5 years: 600 males, 400 females, 834 adults; 166 children (age <18 years)] were studied. Forty-two patients (4.2%; 31 adults, 11 children) developed hepatic artery thrombosis (HAT). Thrombosis in children occurred significantly early (mean 5.4 days) compared with adults (mean 418.7 days, P = 0.0001). Nonthrombotic complications occurred in 30 patients (29 adults, one child). Overall, 13-year patient survival after HAT was 43.2% (72.7% children, 32.9% adults). For nonthrombotic complications, 54.3% of adults died and 69.4% grafts were lost. An overall incidence of 4.2% thrombotic and 3.2% nonthrombotic complications was observed. Rate of HAT was higher in children, but survival was better compared with adults.