Conflicts of Interest The authors have declared no conflicts of interest.
Racial and ethnic disparities in kidney transplantation
Article first published online: 17 DEC 2010
© 2010 The Authors. Transplant International © 2010 European Society for Organ Transplantation
Volume 24, Issue 5, pages 419–424, May 2011
How to Cite
Malek, S. K., Keys, B. J., Kumar, S., Milford, E. and Tullius, S. G. (2011), Racial and ethnic disparities in kidney transplantation. Transplant International, 24: 419–424. doi: 10.1111/j.1432-2277.2010.01205.x
- Issue published online: 5 APR 2011
- Article first published online: 17 DEC 2010
- Received: 30 July 2010 Revision requested: 6 September 2010 Accepted: 15 November 2010 Published online: 17 December 2010
- kidney transplantation;
Success of renal transplantation, as a viable alternative to dialysis, has been tempered by long-standing racial disparities. Ethnic minorities have less access to transplantation, are less likely to be listed for transplantation, and experience a higher rate of graft failure. Reasons for the existing racial disparities at various stages of the transplantation process are complex and multi-factorial. They include a combination of behavioral, social, environmental, and occupational factors, as well as potential intended or unintended discrimination within the healthcare system. Immunologic factors such as human leukocyte antigen matching, composition of the organ donor pool, and patient immune response, all of which affect post-transplantation graft rejection rates and patient survival, also contribute to health disparities between ethnic groups.