Sexual dimorphism of the kidney in the NMRI mouse as shown by Dolichos biflorus agglutinin labelling

Authors


University of Wisconsin, Laboratory of Developmental Biology, Zoology Research, Madison, Wi. 53706, USA

GSF, Institut für Pathologie, 8042 Neuherberg, Germany

Universität München, Institut für Veterinäranatomie, 8000 München, Germany

Summary

The histological affinity pattern of Dolichos biflorus agglutinin (DBA) in kidneys from mice (NMRI, Balb/c, CBA) and rats (Wistar) fixed by perfusion with formalin, Bouin, or HgCl2 was investigated with a horseradish peroxidase conjugate. The animals were examined from fetal stage to adulthood.

Adult female NMRI mice exhibited constant DBA labelling, with DBA binding to cells of the proximal and collecting tubules. Moreover the vascular endothelium of the renal papilla was found to be DBA-positive in 50% of adult female animals. In contrast, there was only very little DBA binding in the kidneys of male adult NMRI mice.

There was no sexual dimorphism in lectin labelling in kidneys from other strains of mice or from rats.

Ancillary