Antimicrobial activity of Hymenaea martiana towards dermatophytes and Cryptococcus neoformans

  1. Ana Cristina Machado De Souza1,
  2. Lucilia Kato2,
  3. Cleuza Conceição Da Silva2,
  4. Amanda Feitosa Cidade2,
  5. Cecilia Maria Alves De Oliveira2,
  6. Maria do Rosário Rodrigues Silva1

Article first published online: 26 JUN 2009

DOI: 10.1111/j.1439-0507.2009.01740.x

Issue

Mycoses

Mycoses

Volume 53, Issue 6, pages 500–503, November 2010

Additional Information

How to Cite

De Souza, A. C. M., Kato, L., Da Silva, C. C., Cidade, A. F., De Oliveira, C. M. A. and Silva, M. d. R. R. (2010), Antimicrobial activity of Hymenaea martiana towards dermatophytes and Cryptococcus neoformans. Mycoses, 53: 500–503. doi: 10.1111/j.1439-0507.2009.01740.x

Author Information

  1. 1

    Laboratorio de Micologia da Universidade Federal de Goiás, Goiás, Brasil

  2. 2

    Laboratório de Química do Instituto de Química/Universidade Federal de Goiás, Goiás, Brazil

*Maria do Rosário Rodrigues Silva, Instituto de Patologia Tropical e Saúde Pública, Rua 235 S/N, Setor Universitário, CEP: 74605-050 Goiânia, Goiás, Brazil. Tel.: +55 62 3209 6109. Fax: +55 62 3521 1839. E-mail: rosario@iptsp.ufg.br

Publication History

  1. Issue published online: 26 JUN 2009
  2. Article first published online: 26 JUN 2009
  3. Accepted for publication 29 April 2009

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Keywords:

  • Hymenaea martiana;
  • antifungal activity;
  • Cryptococcus neoformans;
  • dermatophytes;
  • plants of Cerrado

Summary

The biological activity of crude extract and fractions of Hymenaea martiana was evaluated against a panel of human pathogenic fungi. The crude extracts and hydroalcoholic fractions (E) showed a high activity against Cryptococcus neoformans species complex isolates with MICs between 2 and 64 μg ml−1. The methanolic (C) and butanolic (D) fractions were the most active against Trichopyton rubrum, Trichopyton mentagrophytes and Microsporum canis with MICs between 8 and 256 μg ml−1. None of the extracts was active against the yeast Malassezia furfur, Malassezia obtusa and Malassezia sympodialis.

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