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Micafungin for candidiasis

Authors


Peter G. Pappas, MD, Professor of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, AL, USA, 35294-0006.
Tel.: +1 205 934 9951. Fax: +1 205 934 5155.
E-mail: pappas@uab.edu

Summary

Invasive candidiasis and mucosal candidiasis are among the most important health care associated infections; in its invasive form, candidiasis is associated with substantial morbidity and mortality. Among the currently available antifungal agents, the echinocandins are the among the most potent agents against Candida species. As a class, these agents are well tolerated and rapidly fungicidal. Among the echinocandins, micafungin has been studied most extensively. This paper reviews the results from the largest studies of micafungin among patients with invasive and esophageal candidiasis, and supports the use of echinocandins in this increasingly common disorder.

Ancillary