This research was carried out in the central part of Croatia (Moslavina region).
Efficacy of Ozone and Other Treatment Modalities for Retained Placenta in Dairy Cows
Article first published online: 18 MAY 2012
© 2012 Blackwell Verlag GmbH
Reproduction in Domestic Animals
Volume 48, Issue 1, pages 121–125, February 2013
How to Cite
Zobel, R. and Tkalčić, S. (2013), Efficacy of Ozone and Other Treatment Modalities for Retained Placenta in Dairy Cows. Reproduction in Domestic Animals, 48: 121–125. doi: 10.1111/j.1439-0531.2012.02041.x
Presented manuscript has been read and approved by all included authors. Presented article has not been published previously and will not be submitted for publication elsewhere.
- Issue published online: 15 JAN 2013
- Article first published online: 18 MAY 2012
- Submitted: 4 Nov 2011; Accepted: 15 Apr 2012
Retained placenta is a worldwide recognized clinical condition in puerperal cows, which can significantly affect their health and fertility. Available treatment modalities are often of questionable efficacy or associated with time constraints, practicality or monetary considerations for their wide application in a routine dairy practice. The objective of this study was to compare and assess the efficacy of different treatment options, including a novel ozone treatment, for the retained placenta. Two hundred cows diagnosed with retained placenta were divided into five treatment groups, each receiving a different treatment option. Group A (n = 40) was given a combination treatment of intrauterine ozone and parenteral cephalexin; group B (n = 40) was given intrauterine ozone; group C (n = 40) was given a combination of parenteral cephalexin and intrauterine antibiotic tablets; group D (n = 40) was given only parenteral cephalexin and group E (n = 40) was given parenteral prostaglandins in 11-day intervals. The control group (group Z, n = 200) included cows that gave birth without assistance and were not diagnosed with a retained placenta. The ozone treatment (groups A and B) was found to be the most effective modality resulting in the shortest period of days open, the smallest number of artificial inseminations until pregnancy, the smallest number of animals diagnosed with fever within 10 days post-calving, the highest percentage of animals pregnant within 200 days after calving and the smallest number of animals culled because of infertility, when compared to the other treatment groups. The intrauterine ozone flush therefore has a potential as an efficacious and cost-effective treatment option for retained placenta, with an overall positive effect on puerperal health and fertility in cows.