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  • d’Anglemont d, Fagg LA, Dixon JP, Day K, Leitch HG, Hendrick AG, Zahn D, Franceschini I, Caraty A, Carlton MB, Aparicio SA, Colledge WH, 2007: Hypogonadotropic hypogonadism in mice lacking a functional Kiss1 gene. Proc Natl Acad Sci U S A 104, 1071410719.
  • Barry J, Dubois MP, 1975: Immunofluorescence study of LRF-producing neurons in the cat and the dog. Neuroendocrinology 18, 290298.
  • Belda M, Covenas R, Narvaez JA, Aguirre JA, Tramu G, 2000: Distribution of luteinizing hormone-releasing hormone in the upper brainstem and diencephalon of the cat: an immunocytochemical study. Brain Res Bull 51, 281291.
  • Bienvenu T, Carrié A, de Roux N, Vinet M-C, Jonveaux P, Cuvert P, Villard L, Arzimanoglou A, Beldjord C, Fontes M, Tardieu M, Chelly J, 2000: MECP2 mutations account for most cases of typical forms of Rett syndrome. Hum Mol Genet 9, 13771384.
  • Birmingham A, Anderson EM, Reynolds A, Ilsley-Tyree D, Leake D, Fedorov Y, Baskerville S, Maksimova E, Robinson K, Karpilow J, Marshall WS, Khvorova A, 2006: 3′ UTR seed matches, but not overall identity, are associated with RNAi off-targets. Nat Methods 3, 199204.
  • Boudreau RL, Spengler RM, Davidson BL, 2011: Rational design of therapeutic siRNAs: minimizing off-targeting potential to improve the safety of RNAi therapy for Huntington’s disease. Mol Ther 19, 21692177.
  • Broadwell RD, Brightman MW, 1976: Entry of peroxidase into neurons of the central and peripheral nervous systems from extracerebral and cerebral blood. J Comp Neurol 166, 257283.
  • Chen YH, Chang M, Davidson BL, 2009: Molecular signatures of disease brain endothelia provide new sites for CNS-directed enzyme therapy. Nat Med 15, 12151218.
  • Chi JT, Chang HY, Wang NN, Chang DS, Dunphy N, Brown PO, 2003: Genomewide view of gene silencing by small interfering RNAs. Proc Natl Acad Sci U S A 100, 63436346.
  • Clarkson J, d’Anglemont d, Moreno AS, Colledge WH, Herbison AE, 2008: Kisspeptin-GPR54 signaling is essential for preovulatory gonadotropin-releasing hormone neuron activation and the luteinizing hormone surge. J Neurosci 28, 86918697.
  • Clarkson J, d’Anglemont d, Colledge WH, Caraty A, Herbison AE, 2009: Distribution of kisspeptin neurones in the adult female mouse brain. J Neuroendocrinol 21, 673682.
  • Cullen BR, 2005: RNAi the natural way. Nat Genet 37, 11631165.
  • Dissen GA, Lomniczi A, Heger S, Neff TL, Ojeda SR, 2012a: Hypothalamic enhanced at puberty 1 (EAP1) is required for menstrual cyclicity in non-human primates. Endocrinology 153, 350361.
  • Dissen GA, McBride JL, Lomniczi A, Matagne V, Dorfman M, Neff TL, Galimi F, Ojeda SR, 2012b: Using lentiviral vectors as delivery vehicles for gene therapy. In: Morozov A (ed.), Controlled Genetic Manipulations. Springer Science + Business Media in their Neuromethods series formerly published by Humana Press, Bethesda, MD, pp. 6996.
  • Fedorov Y, Anderson EM, Birmingham A, Reynolds A, Karpilow J, Robinson K, Leake D, Marshall WS, Khvorova A, 2006: Off-target effects by siRNA can induce toxic phenotype. RNA 12, 11881196.
  • Funes S, Hedrick j, Vassileva G, Markowitz L, Abbondanzo S, Golovko A, Yang S, Monsma FJ, Gustafson EL, 2003: The KiSS-1 receptor GPR54 is essential for the development of the murine reproductive system. Biochem Biophys Res Commun 312, 13571363.
  • Gaytan F, Gaytan M, Castellano JM, Romero M, Roa J, Aparicio B, Garrido N, Sanchez-Criado JE, Millar RP, Pellicer A, Fraser HM, Tena-Sempere M, 2009: KiSS-1 in the mammalian ovary: distribution of kisspeptin in human and marmoset and alterations in KiSS-1 mRNA levels in a rat model of ovulatory dysfunction. Am J Physiol Endocrinol Metab 296, E520E531.
  • Gottsch ML, Cunningham MJ, Smith JT, Popa SM, Acohido BV, Crowley WF, Seminara S, Clifton DK, Steiner RA, 2004: A role for kisspeptins in the regulation of gonadotropin secretion in the mouse. Endocrinology 145, 40734077.
  • Gregory RI, Yan KP, Amuthan G, Chendrimada T, Doratotaj B, Cooch N, Shiekhattar R, 2004: The Microprocessor complex mediates the genesis of microRNAs. Nature 432, 235240.
  • Guo H, Ingolia NT, Weissman JS, Bartel DP, 2010: Mammalian microRNAs predominantly act to decrease target mRNA levels. Nature 466, 835840.
  • Heger S, Mastronardi C, Dissen GA, Lomniczi A, Cabrera R, Roth CL, Jung H, Galimi F, Sippell W, Ojeda SR, 2007: Enhanced at puberty 1 (EAP1) is a new transcriptional regulator of the female neuroendocrine reproductive axis. J Clin Invest 117, 21452154.
  • Herbison AE, 2006: Physiology of the gonadotropin-releasing hormone neuronal network. In: Neill JD (ed.), Physiology of Reproduction, 3rd edn. Academic Press/Elsevier, San Diego, pp. 14151482.
  • Herde MK, Geist K, Campbell RE, Herbison AE, 2011: Gonadotropin-releasing hormone neurons extend complex highly branched dendritic trees outside the blood-brain barrier. Endocrinology 152, 38323841.
  • Jackson AL, Bartz SR, Schelter J, Kobayashi SV, Burchard J, Mao M, Li B, Cavet G, Linsley PS, 2003: Expression profiling reveals off-target gene regulation by RNAi. Nat Biotechnol 21, 635637.
  • Kaplitt MG, Leone P, Samulski RJ, Xiao X, Pfaff DW, O’Malley KL, During MJ, 1994: Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brain. Nat Genet 8, 148154.
  • Khvorova A, Reynolds A, Jayasena SD, 2003: Functional siRNAs and miRNAs exhibit strand bias. Cell 115, 209216.
  • Kordon C, Drouva SV, Martínez de la Escalera G, Weiner RI, 1994: Role of classic and peptide neuromediators in the neuroendocrine regulation of luteinizing hormone and prolactin. In: Knobil E, Neill JD (eds), The Physiology of Reproduction, 2nd edn, Vol. 1. Raven Press, New York, pp. 16211681.
  • Krol J, Loedige I, Filipowicz W, 2010: The widespread regulation of microRNA biogenesis, function and decay. Nat Rev Genet 11, 597610.
  • Lee Y, Ahn C, Han J, Choi H, Kim J, Yim J, Lee J, Provost P, Radmark O, Kim S, Kim VN, 2003: The nuclear RNase III Drosha initiates microRNA processing. Nature 425, 415419.
  • Lehman MN, Coolen LM, Goodman RL, 2010: Minireview: kisspeptin/neurokinin B/dynorphin (KNDy) cells of the arcuate nucleus: a central node in the control of gonadotropin-releasing hormone secretion. Endocrinology 151, 34793489.
  • Lewis BP, Burge CB, Bartel DP, 2005: Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 120, 1520.
  • McCown TJ, Xiao X, Li J, Breese GR, Samulski RJ, 1996: Differential and persistent expression patterns of CNS gene transfer by an adeno-associated virus (AAV) vector. Brain Res 713, 99107.
  • Mingozzi F, High KA, 2011: Therapeutic in vivo gene transfer for genetic disease using AAV: progress and challenges. Nat Rev Genet 12, 341355.
  • Mueller C, Flotte TR, 2008: Clinical gene therapy using recombinant adeno-associated virus vectors. Gene Ther 15, 858863.
  • Muller OJ, Kaul F, Weitzman MD, Pasqualini R, Arap W, Kleinschmidt JA, Trepel M, 2003: Random peptide libraries displayed on adeno-associated virus to select for targeted gene therapy vectors. Nat Biotechnol 21, 10401046.
  • Navarro VM, Gottsch ML, Wu M, Garcia-Galiano D, Hobbs SJ, Bosch MA, Pinilla L, Clifton DK, Dearth A, Ronnekleiv OK, Braun RE, Palmiter RD, Tena-Sempere M, Alreja M, Steiner RA, 2011: Regulation of NKB pathways and their roles in the control of Kiss1 neurons in the arcuate nucleus of the male mouse. Endocrinology 152, 42654275.
  • Ojeda SR, Terasawa E, 2002: Neuroendocrine regulation of puberty. In: Pfaff D, Arnold A, Etgen A, Fahrbach S, Moss R, Rubin R (eds), Hormones, Brain and Behavior, Vol. 4. Elsevier, New York, pp. 589659.
  • Ojeda SR, Prevot V, Heger S, Lomniczi A, Dziedzic B, Mungenast A, 2003: Glia-to neuron signaling and the neuroendocrine control of female puberty. Ann Med 35, 244255.
  • Ojeda SR, Lomniczi A, Loche A, Matagne V, Kaidar G, Sandau US, Dissen GA, 2010: The transcriptional control of female puberty. Brain Res 1364, 164174.
  • Perabo L, Goldnau D, White K, Endell J, Boucas J, Humme S, Work LM, Janicki H, Hallek M, Baker AH, Buning H, 2006: Heparan sulfate proteoglycan binding properties of adeno-associated virus retargeting mutants and consequences for their in vivo tropism. J Virol 80, 72657269.
  • Plant TM, Witchel SF, 2006: Puberty in nonhuman primates and humans. In: Neill JD (ed.), The Physiology of Reproduction, 3rd edn. Academic Press/Elsevier, San Diego, pp. 21772230.
  • Provost P, Dishart D, Doucet J, Frendewey D, Samuelsson B, Radmark O, 2002: Ribonuclease activity and RNA binding of recombinant human Dicer. EMBO J 21, 58645874.
  • Schwarz DS, Hutvágner G, Du T, Xu Z, Aronin N, Zamore PD, 2003: Asymmetry in the assembly of the RNAi enzyme complex. Cell 115, 199208.
  • Semizarov D, Frost L, Sarthy A, Kroeger P, Halbert DN, Fesik SW, 2003: Specificity of short interfering RNA determined through gene expression signatures. Proc Natl Acad Sci U S A 100, 63476352.
  • Semple RK, Achermann JC, Ellery J, Farooqi IS, Karet FE, Stanhope RG, O’Rahilly S, Aparicio SA, 2005: Two novel missense mutations in G protein-coupled receptor 54 in a patient with hypogonadotropic hypogonadism. J Clin Endocrinol Metab 90, 18491855.
  • Silveira LG, Tusset C, Latronico AC, 2010: Impact of mutations in kisspeptin and neurokinin B signaling pathways on human reproduction. Brain Res 1364, 7280.
  • Simerly RB, 2002: Wired for reproduction: organization and development of sexually dimorphic circuits in the mammalian forebrain. Ann Rev Neurosci 25, 507536.
  • Su AI, Wiltshire T, Batalov S, Lapp H, Ching KA, Block D, Zhang J, Soden R, Hayakawa M, Kreiman G, Cooke MP, Walker JR, Hogenesch JB, 2004: A gene atlas of the mouse and human protein-encoding transcriptomes. Proc Natl Acad Sci U S A 101, 60626067.
  • Terasawa E, Fernandez DL, 2001: Neurobiological mechanisms of the onset of puberty in primates. Endocr Rev 22, 111151.
  • Topaloglu AK, Reimann F, Guclu M, Yalin AS, Kotan LD, Porter KM, Serin A, Mungan NO, Cook JR, Ozbek MN, Imamoglu S, Akalin NS, Yuksel B, O’Rahilly S, Semple RK, 2008: TAC3 and TACR3 mutations in familial hypogonadotropic hypogonadism reveal a key role for Neurokinin B in the central control of reproduction. Nat Genet 41, 354358.
  • Wakabayashi Y, Nakada T, Murata K, Ohkura S, Mogi K, Navarro VM, Clifton DK, Mori Y, Tsukamura H, Maeda K, Steiner RA, Okamura H, 2010: Neurokinin B and dynorphin A in kisspeptin neurons of the arcuate nucleus participate in generation of periodic oscillation of neural activity driving pulsatile gonadotropin-releasing hormone secretion in the goat. J Neurosci 30, 31243132.
  • Work LM, Nicklin SA, White SJ, Baker AH, 2002: Use of phage display to identify novel peptides for targeted gene therapy. Methods Enzymol 346, 157176.
  • Work LM, Buning H, Hunt E, Nicklin SA, Denby L, Britton N, Leike K, Odenthal M, Drebber U, Hallek M, Baker AH, 2006: Vascular bed-targeted in vivo gene delivery using tropism-modified adeno-associated viruses. Mol Ther 13, 683693.
  • Wu Z, Asokan A, Samulski RJ, 2006: Adeno-associated virus serotypes: vector toolkit for human gene therapy. Mol Ther 14, 316327.
  • Xiao X, Li J, Samulski RJ, 1996: Efficient long-term gene transfer into muscle tissue of immunocompetent mice by adeno-associated virus vector. J Virol 70, 80988108.