Bernadette Ricciardo, MBBS. Alan Irvine, FRCPI. Michael McDermott, FRCPI. John Ryan, FRCPI. Sinead Collins, FRCPI.
A case of congenital solitary Langerhans cell histiocytoma
Article first published online: 26 FEB 2010
© 2010 The Authors. Australasian Journal of Dermatology © 2010 The Australasian College of Dermatologists
Australasian Journal of Dermatology
Volume 52, Issue 2, pages e1–e3, May 2011
How to Cite
Ricciardo, B., Irvine, A., McDermott, M., Ryan, J. and Collins, S. (2011), A case of congenital solitary Langerhans cell histiocytoma. Australasian Journal of Dermatology, 52: e1–e3. doi: 10.1111/j.1440-0960.2010.00625.x
- Issue published online: 26 FEB 2010
- Article first published online: 26 FEB 2010
- Submitted 12 December 2009; accepted 22 December 2009.
- congenital self-healing Langerhans cell histiocytosis;
- congenital self-healing reticulohistiocytosis;
- congenital solitary histiocytoma;
- Hashimoto–Pritzker disease
A newborn baby boy was referred to the Paediatric Dermatology Unit with a solitary asymptomatic nodule overlying his right nasolabial fold. Complete physical examination, full blood count, serum chemistry, liver function tests and baseline imaging were unremarkable. Histopathological examination showed an atypical dermal infiltrate of mononuclear cells that stained positive with CD1a and S100. A diagnosis of congenital solitary Langerhans cell histiocytoma was made. The lesion completely resolved by 4 months of age. The baby is now 15 months old and repeat systemic evaluation has remained normal.