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Angiolymphoid hyperplasia with eosinophilia and Kimura's disease coexisting in the same patient: Evidence for a spectrum of disease


  • Xiao-kun Liu, MD. Jun Ren, MD, PhD. Xiao-hui Wang, MD, PhD. Xin-sheng Li, MD. Hai-ping Zhang, MD. Kang Zeng, MD.

  • Conflicts of interest: None declared.

Dr Jun Ren, Department of Dermatology, Zhongshan Hospital of Xiamen University, No. 201 Hubin South Road, Xiamen, Fujian 361004, China. Email:


The relationship between angiolymphoid hyperplasia with eosinophilia (ALHE) and Kimura's disease has always been contentious. Initially, ALHE and Kimura's disease were thought to be conditions within the same disease spectrum, but it is now widely accepted that they are two separate disease entities. The two lesions may coexist in one patient. Thus, ALHE and Kimura's disease may be different manifestations of the one disease.