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New insights in naevogenesis: Number, distribution and dermoscopic patterns of naevi in the elderly

Authors

  • Peter Piliouras,

    Corresponding author
    1. Dermatology Research Centre, School of Medicine, The University of Queensland
    2. James Cook University Medical School, Townsville, Queensland, Australia
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  • Stephen Gilmore,

    Corresponding author
    1. Dermatology Research Centre, School of Medicine, The University of Queensland
    2. Queensland Institute of Dermatology, Greenslopes Hospital, Brisbane
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  • Elisabeth M Wurm,

    1. Dermatology Research Centre, School of Medicine, The University of Queensland
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  • H Peter Soyer,

    1. Dermatology Research Centre, School of Medicine, The University of Queensland
    2. Queensland Institute of Dermatology, Greenslopes Hospital, Brisbane
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  • Iris Zalaudek

    1. Division of Dermatology, Medical University of Graz, Graz, Austria
    2. Dermatology Unit, 1st Medical Department, Arcispedale Santa Maria Nuova, Reggio Emilia, Italy
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  • Peter Piliouras, MBBS. Stephen Gilmore, FACD. Elisabeth M. Wurm, MD. H Peter Soyer, FACD. Iris Zalaudek, MD.

Associate Professor Stephen Gilmore, Dermatology Research Centre, The University of Queensland, School of Medicine, Princess Alexandra Hospital, Brisbane, Queensland, 4102, Australia. Email: s.gilmore1@uq.edu.au

ABSTRACT

Background/Objectives:  It is well recognized that the number and patterns of acquired melanocytic naevi vary with age, but little is known about naevus patterns in the elderly. This is a cross-sectional study assessing the prevalence, dermoscopic pattern and anatomical distribution of naevus subtypes in a stratified cohort aged between 60 and 89 years.

Methods:  Fifty-nine patients who attended the Queensland Institute of Dermatology were recruited randomly and evenly distributed into three age groups: 60–69 years; 70–79 years; and 80–89 years. For each participant, total naevus count and morphological naevus types were recorded with respect to age, sex and anatomical location. Flat (Clark's) naevi were further subclassified according to the dermoscopic pattern as reticular, globular or structureless.

Results:  Using non-parametric methods, naevus counts in the elderly decreased due to the disappearance of reticular naevi (P < 0.05). By contrast, structureless and intradermal (Unna's and Miescher's) naevi seemed to persist even into older age. Naevi on the trunk, limbs, head and neck represented 57.6%, 31.0% and 11.3%, respectively. Notably, no reticular naevi were found on the head and neck area.

Conclusions:  There is a progressive reduction in total naevus counts with advancing age with respect to a cohort aged greater than 60 years.

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