Juber Hafiji, MB ChB, MRCP (UK). Patrick Deegan, MD MRCPI, FRCPath. Rebecca Brais, MRCPath. Paul Norris, MA, FRCP.
Warfarin-induced calciphylaxis successfully treated with sodium thiosulphate
Article first published online: 16 FEB 2012
© 2012 The Authors. Australasian Journal of Dermatology © 2012 The Australasian College of Dermatologists
Australasian Journal of Dermatology
Volume 54, Issue 2, pages 133–135, May 2013
How to Cite
Hafiji, J., Deegan, P., Brais, R. and Norris, P. (2013), Warfarin-induced calciphylaxis successfully treated with sodium thiosulphate. Australasian Journal of Dermatology, 54: 133–135. doi: 10.1111/j.1440-0960.2011.00861.x
- Issue published online: 14 APR 2013
- Article first published online: 16 FEB 2012
- Submitted 15 October 2011; accepted 12 November 2011.
- sodium thiosulphate;
- vitamin K2;
Calciphylaxis is a rare life-threatening form of skin necrosis. Although traditionally observed in patients with end-stage renal disease and/or hyperparathyroidism, calciphylaxis has also been reported to occur in ‘non-traditional’ patients with normal renal and parathyroid function. We report a case of warfarin-induced calciphylaxis treated successfully with sodium thiosulphate and discuss the role of Vitamin K2 as a potential therapeutic option in the management of warfarin-induced calciphylaxis.