Aya Kakizaki, MD. Taku Fujimura, MD, PhD. Masato Mizuashi, MD. Akiko Watabe, MD. Yumi Kambayashi MD. Setsuya Aiba, MD, PhD.
Successful treatment of syringotropic CD8+ mycosis fungoides accompanied by hypohidrosis with vorinostat and retinoids
Article first published online: 11 SEP 2012
© 2012 The Authors Australasian Journal of Dermatology © 2012 The Australasian College of Dermatologists
Australasian Journal of Dermatology
Volume 54, Issue 4, pages e82–e84, November 2013
How to Cite
Kakizaki, A., Fujimura, T., Mizuashi, M., Watabe, A., Kambayashi, Y. and Aiba, S. (2013), Successful treatment of syringotropic CD8+ mycosis fungoides accompanied by hypohidrosis with vorinostat and retinoids. Australasian Journal of Dermatology, 54: e82–e84. doi: 10.1111/j.1440-0960.2012.00944.x
Conflicts of interest: None.
- Issue published online: 25 OCT 2013
- Article first published online: 11 SEP 2012
- Manuscript Accepted: 1 JUL 2012
- Manuscript Received: 22 MAY 2012
We describe a 34-year-old Japanese man with syringotropic CD8+ mycosis fungoides (MF) accompanied by hypohidrosis who was treated with vorinostat and retinoids. Interestingly, immunohistochemical staining for dermcidin revealed a decrease of sweat in the eccrine glands, and a sweat test by the iodine starch method proved hypohidrosis in the MF-affected areas. Six months after treatment with this combination therapy, the patient's advanced MF was under control.