Presented at the Australian Physiological and Pharmacological Society Symposium Stretch-induced Muscle Damage in Sport and Disease, September 2003. The papers in these proceedings were peer reviewed under the supervision of the APPS Editor. The papers are being published with the permission of the APPS and were initially published on the APPS website (http://www.apps.org.au).
POPPING SARCOMERE HYPOTHESIS EXPLAINS STRETCH-INDUCED MUSCLE DAMAGE
Version of Record online: 3 AUG 2004
Clinical and Experimental Pharmacology and Physiology
Volume 31, Issue 8, pages 541–545, August 2004
How to Cite
Morgan, D. L. and Proske, U. (2004), POPPING SARCOMERE HYPOTHESIS EXPLAINS STRETCH-INDUCED MUSCLE DAMAGE. Clinical and Experimental Pharmacology and Physiology, 31: 541–545. doi: 10.1111/j.1440-1681.2004.04029.x
- Issue online: 3 AUG 2004
- Version of Record online: 3 AUG 2004
- Received 16 January 2004; revision 4 May 2004; accepted 20 May 2004.
- contraction-induced injury;
- eccentric contractions;
- human exercise;
1. Exercise that involves stretching a muscle while active cause microscopic areas of damage, delayed onset muscle soreness and adaptation to withstand subsequent similar exercise.
2. Longer muscle lengths are associated with greater damage and recent animal experiments show that it is the length relative to optimum that determines the damage.
3. In humans, walking down stairs, taking two at a time, increases the length of the muscle during the lengthening and increases the delayed onset muscle soreness.
4. The observed pattern of damage is consistent with explanations based on sarcomere length instabilities.
5. The pattern of adaptation is consistent with the number of sarcomeres in series in a muscle being modulated by exercise, especially the range of muscle lengths over which eccentric exercise regularly occurs.