SPECIES VARIABILITY IN CARDIOVASCULAR RESEARCH: THE EXAMPLE OF ADRENOCORTICOTROPHIN-INDUCED HYPERTENSION

Authors


  • Presented at a symposium in honour of Lawrie Beilin held in conjunction with the High Blood Pressure Research Council of Australia Annual Scientific Meeting, Melbourne, 6–7 December 2005. The papers in these proceedings have been peer reviewed.

Judith A Whitworth, The John Curtin School of Medical Research, The Australian National University, Canberra, ACT 0200, Australia. Email: director@jcsmr.anu.edu.au

SUMMARY

  • 1Lawrie Beilin has contributed greatly to international hypertension research through both animal and human studies.
  • 2Animals are used in biomedical research to gain insights that can be extrapolated ultimately to humans.
  • 3A simple experimental manipulation, adrenocorticotrophin (ACTH) administration, has a range of different cardiovascular effects in different species.
  • 4Caution should be exercised in extrapolating data from animals to humans.

Ancillary