This paper has been peer reviewed
ARTERIAL STIFFNESS AND CARDIOVASCULAR OUTCOME
Article first published online: 18 JUN 2007
Clinical and Experimental Pharmacology and Physiology
Volume 34, Issue 7, pages 647–651, July 2007
How to Cite
Zoungas, S. and Asmar, R. P. (2007), ARTERIAL STIFFNESS AND CARDIOVASCULAR OUTCOME. Clinical and Experimental Pharmacology and Physiology, 34: 647–651. doi: 10.1111/j.1440-1681.2007.04654.x
- Issue published online: 18 JUN 2007
- Article first published online: 18 JUN 2007
- Received 7 November 2006; revision 8 January 2007; accepted 11 February 2007.
- arterial compliance;
- arterial stiffness;
- augmentation index;
- cardiovascular events;
- cardiovascular risk;
- pulse wave velocity
- 1Studies have reported an association between arterial function indices and cardiovascular risk factors, as well as the risk of incident cardiovascular events, including coronary heart disease and stroke.
- 2The data are overwhelmingly in favour of an independent role for aortic pulse wave velocity in predicting fatal and non-fatal cardiovascular events in healthy and diseased populations and in the evaluation of cardiovascular risk.
- 3Augmentation index may independently predict all-cause mortality and cardiovascular events in coronary and end-stage renal disease patients, but some outcome studies have questioned its usefulness in hypertensive subjects and dialysis patients.
- 4Systemic arterial compliance, to this time, has not been shown to independently predict cardiovascular outcome.
- 5Future cardiovascular risk is greatly modified by prior disease and risk factors; the greatest additional value in measuring arterial stiffness and compliance may be in those with little or no end-organ disease.