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Keywords:

  • arterial compliance;
  • arterial stiffness;
  • augmentation index;
  • cardiovascular events;
  • cardiovascular risk;
  • pulse wave velocity

SUMMARY

  • 1
    Studies have reported an association between arterial function indices and cardiovascular risk factors, as well as the risk of incident cardiovascular events, including coronary heart disease and stroke.
  • 2
    The data are overwhelmingly in favour of an independent role for aortic pulse wave velocity in predicting fatal and non-fatal cardiovascular events in healthy and diseased populations and in the evaluation of cardiovascular risk.
  • 3
    Augmentation index may independently predict all-cause mortality and cardiovascular events in coronary and end-stage renal disease patients, but some outcome studies have questioned its usefulness in hypertensive subjects and dialysis patients.
  • 4
    Systemic arterial compliance, to this time, has not been shown to independently predict cardiovascular outcome.
  • 5
    Future cardiovascular risk is greatly modified by prior disease and risk factors; the greatest additional value in measuring arterial stiffness and compliance may be in those with little or no end-organ disease.