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  • Allshire, R. C. & Karpen, G. H. 2008. Epigenetic regulation of centromeric chromatin: old dogs, new tricks? Nat. Rev. Genet. 9, 923937.
  • Allshire, R. C., Nimmo, E. R., Ekwall, K., Javerzat, J. P. & Cranston, G. 1995. Mutations derepressing silent centromeric domains in fission yeast disrupt chromosome segregation. Genes Dev. 9, 218233.
  • Angers, S., Li, T., Yi, X., Maccoss, M. J., Moon, R. T. & Zheng, N. 2006. Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery. Nature 443, 590593.
  • Bannister, A. J., Zegerman, P., Partridge, J. F., Miska, E. A., Thomas, J. O., Allshire, R. C. & Kouzarides, T. 2001. Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain. Nature 410, 120124.
  • Bayne, E. H., Portoso, M., Kagansky, A., Kos-Braun, I. C., Urano, T., Ekwall, K., Alves, F., Rappsilber, J. & Allshire, R. C. 2008. Splicing factors facilitate RNAi-directed silencing in fission yeast. Science 322, 602606.
  • Bayne, E. H., White, S. A., Kagansky, A., Bijos, D. A., Sanchez-Pulido, L., Hoe, K.-L., Kim, D.-U., Park, H.-O., Ponting, C. P., Rappsilber, J. & Allshire, R. C. 2010. Stc1: a critical link between RNAi and chromatin modification required for heterochromatin integrity. Cell 140, 666677.
  • Bourc’his, D. & Voinnet, O. 2010. A small-RNA perspective on gametogenesis, fertilization, and early zygotic development. Science 330, 617622.
  • Buhler, M., Verdel, A. & Moazed, D. 2006. Tethering RITS to a nascent transcript initiates RNAi- and heterochromatin-dependent gene silencing. Cell 125, 873886.
  • Buker, S. M., Iida, T., Buhler, M., Villén, J., Gygi, S. P., Nakayama, J. & Moazed, D. 2007. Two different Argonaute complexes are required for siRNA generation and heterochromatin assembly in fission yeast. Nat. Struct. Mol. Biol. 14, 200207.
  • Chen, E. S., Zhang, K., Nicolas, E., Cam, H. P., Zofall, M. & Grewal, S. I. 2008. Cell cycle control of centromeric repeat transcription and heterochromatin assembly. Nature 451, 734737.
  • Chinen, M., Morita, M., Fukumura, K. & Tani, T. 2010. Involvement of the spliceosomal U4 small nuclear RNA in heterochromatic gene silencing at fission yeast centromeres. J. Biol. Chem. 285, 56305638.
  • Cogoni, C. & Macino, G. 1999. Gene silencing in Neurospora crassa requires a protein homologous to RNA-dependent RNA polymerase. Nature 399, 166169.
  • Colmenares, S. U., Buker, S. M., Buhler, M., Dlakic, M. & Moazed, D. 2007. Coupling of double-stranded RNA synthesis and siRNA generation in fission yeast RNAi. Mol. Cell 27, 449461.
  • Couzin, J. 2002. Breakthrough of the year. Small RNAs make big splash. Science 298, 22962297.
  • Dalmay, T., Hamilton, A., Rudd, S., Angell, S. & Baulcombe, D. C. 2000. An RNA-dependent RNA polymerase gene in Arabidopsis is required for posttranscriptional gene silencing mediated by a transgene but not by a virus. Cell 101, 543553.
  • Djupedal, I., Portoso, M., Spahr, H., Spåhr, H., Bonilla, C., Gustafsson, C. M., Allshire, R. C. & Ekwall, K. 2005. RNA Pol II subunit Rpb7 promotes centromeric transcription and RNAi-directed chromatin silencing. Genes Dev. 19, 23012306.
  • Doe, C. L., Wang, G., Chow, C., Fricker, M. D., Singh, P. B. & Mellor, E. J. 1998. The fission yeast chromo domain encoding gene chp1+ is required for chromosome segregation and shows a genetic interaction with alpha-tubulin. Nucleic Acids Res. 26, 42224229.
  • Dormann, H. L., Tseng, B. S., Allis, C. D., Funabiki, H. & Fischle, W. 2006. Dynamic regulation of effector protein binding to histone modifications: the biology of HP1 switching. Cell Cycle 5, 28422851.
  • Ekwall, K., Javerzat, J. P., Lorentz, A., Schmidt, H., Cranston, G. & Allshire, R. 1995. The chromodomain protein Swi6: a key component at fission yeast centromeres. Science 269, 14291431.
  • Ekwall, K., Nimmo, E. R., Javerzat, J. P., Borgstrøm, B., Egel, R., Cranston, G. & Allshire, R. 1996. Mutations in the fission yeast silencing factors clr4+ and rik1+ disrupt the localisation of the chromo domain protein Swi6p and impair centromere function. J. Cell Sci. 109, 26372648.
  • Gerace, E. L., Halic, M. & Moazed, D. 2010. The methyltransferase activity of Clr4Suv39h triggers RNAi independently of histone H3K9 methylation. Mol. Cell 39, 360372.
  • Ghildiyal, M. & Zamore, P. D. 2009. Small silencing RNAs: an expanding universe. Nat. Rev. Genet. 10, 94108.
  • Gullerova, M. & Proudfoot, N. J. 2008. Cohesin complex promotes transcriptional termination between convergent genes in S. pombe. Cell 132, 983995.
  • Halic, M. & Moazed, D. 2010. Dicer-independent primal RNAs trigger RNAi and heterochromatin formation. Cell 140, 504516.
  • Hammond, S. M., Bernstein, E., Beach, D. & Hannon, G. J. 2000. An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells. Nature 404, 293296.
  • Hannon, G. J. 2002. RNA interference. Nature 418, 244251.
  • Hayashi, M. T., Takahashi, T. S., Nakagawa, T., Nakayama, J. & Masukata, H. 2009. The heterochromatin protein Swi6/HP1 activates replication origins at the pericentromeric region and silent mating-type locus. Nat. Cell Biol. 11, 357362.
  • Hong, E. J., Villen, J., Gerace, E. L., Gygi, S. P. & Moazed, D. 2005. A cullin E3 ubiquitin ligase complex associates with Rik1 and the Clr4 histone H3-K9 methyltransferase and is required for RNAi-mediated heterochromatin formation. RNA. Biol. 2, 106111.
  • Horn, P. J., Bastie, J. N. & Peterson, C. L. 2005. A Rik1-associated, cullin-dependent E3 ubiquitin ligase is essential for heterochromatin formation. Genes Dev. 19, 17051714.
  • Huisinga, K. L. & Elgin, S. C. 2009. Small RNA-directed heterochromatin formation in the context of development: what flies might learn from fission yeast. Biochim. Biophys. Acta 1789, 316.
  • Iida, T., Nakayama, J. & Moazed, D. 2008. siRNA-mediated heterochromatin establishment requires HP1 and is associated with antisense transcription. Mol. Cell 31, 178189.
  • Irvine, D. V., Zaratiegui, M., Tolia, N. H., Goto, D. B., Chitwood, D. H., Vaughn, M. W., Joshua-Tor, L. & Martienssen, R. A. 2006. Argonaute slicing is required for heterochromatic silencing and spreading. Science 313, 11341137.
  • Ivanova, A. V., Bonaduce, M. J., Ivanov, S. V. & Klar, A. J. 1998. The chromo and SET domains of the Clr4 protein are essential for silencing in fission yeast. Nat. Genet. 19, 192195.
  • Jia, S., Kobayashi, R. & Grewal, S. I. 2005. Ubiquitin ligase component Cul4 associates with Clr4 histone methyltransferase to assemble heterochromatin. Nat. Cell Biol. 7, 10071013.
  • Jia, S., Noma, K. & Grewal, S. I. 2004. RNAi-independent heterochromatin nucleation by the stress-activated ATF/CREB family proteins. Science 304, 19711976.
  • Kagansky, A., Folco, H. D., Almeida, R., Pidoux, A. L., Boukaba, A., Simmer, F., Urano, T., Hamilton, G. L. & Allshire, R. C. 2009. Synthetic heterochromatin bypasses RNAi and centromeric repeats to establish functional centromeres. Science 324, 17161719.
  • Kato, H., Goto, D. B., Martienssen, R. A., Urano, T., Furukawa, K. & Murakami, Y. 2005. RNA polymerase II is required for RNAi-dependent heterochromatin assembly. Science 309, 467469.
  • Kidner, C. A. & Martienssen, R. A. 2004. Spatially restricted microRNA directs leaf polarity through ARGONAUTE1. Nature 428, 8184.
  • Klar, A. J. 2007. Lessons learned from studies of fission yeast mating-type switching and silencing. Annu. Rev. Genet. 41, 213236.
  • Kloc, A., Zaratiegui, M., Nora, E. & Martienssen, R. 2008. RNA interference guides histone modification during the S phase of chromosomal replication. Curr. Biol. 18, 490495.
  • Kouzarides, T. 2007. Chromatin modifications and their function. Cell 128, 693705.
  • Lewis, Z. A., Adhvaryu, K. K., Honda, S., Shiver, A. L., Knip, M., Sack, R. & Selker, E. U. 2010. DNA methylation and normal chromosome behavior in Neurospora depend on five components of a histone methyltransferase complex, DCDC. PLoS Genet. 6, e1001196.
  • Li, F., Goto, D. B., Zaratiegui, M., Tang, X., Martienssen, R. & Cande, W. Z. 2005. Two novel proteins, dos1 and dos2, interact with rik1 to regulate heterochromatic RNA interference and histone modification. Curr. Biol. 15, 14481457.
  • Li, F., Huarte, M., Zaratiegui, M., Vaughn, M. W., Shi, Y., Martienssen, R. & Cande, W. Z. 2008. Lid2 is required for coordinating H3K4 and H3K9 methylation of heterochromatin and euchromatin. Cell 135, 272283.
  • Li, F., Martienssen, R. & Cande, W. Z. 2011. Coordination of DNA replication and histone modification by the Rik1-Dos2 complex. Nature 475, 244248.
  • Li, T., Chen, X., Garbutt, K. C., Zhou, P. & Zheng, N. 2006. Structure of DDB1 in complex with a paramyxovirus V protein: viral hijack of a propeller cluster in ubiquitin ligase. Cell 124, 105117.
  • Malecova, B. & Morris, K. V. 2010. Transcriptional gene silencing through epigenetic changes mediated by non-coding RNAs. Curr. Opin. Mol. Ther. 12, 214222.
  • Mandel, C. R., Bai, Y. & Tong, L. 2008. Protein factors in pre-mRNA 3′-end processing. Cell. Mol. Life Sci. 65, 10991122.
  • Martienssen, R. A., Zaratiegui, M. & Goto, D. B. 2005. RNA interference and heterochromatin in the fission yeast Schizosaccharomyces pombe. Trends Genet. 21, 450456.
  • Matzke, M., Kanno, T., Daxinger, L., Huettel, B. & Matzke, A. J. 2009. RNA-mediated chromatin-based silencing in plants. Curr. Opin. Cell Biol. 21, 367376.
  • Mello, C. C. & Conte Jr, D. 2004. Revealing the world of RNA interference. Nature 431, 338342.
  • Motamedi, M. R., Hong, E. J., Li, X., Gerber, S., Denison, C., Gygi, S. & Moazed, D. 2008. HP1 proteins form distinct complexes and mediate heterochromatic gene silencing by nonoverlapping mechanisms. Mol. Cell 32, 778790.
  • Motamedi, M. R., Verdel, A., Colmenares, S. U., Gerber, S. A., Gygi, S. P. & Moazed, D. 2004. Two RNAi complexes, RITS and RDRC, physically interact and localize to noncoding centromeric RNAs. Cell 119, 789802.
  • Nakayama, J., Rice, J. C., Strahl, B. D., Allis, C. D. & Grewal, S. I. 2001. Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assembly. Science 292, 110113.
  • Noma, K., Sugiyama, T., Cam, H., Verdel, A., Zofall, M., Jia, S., Moazed, D. & Grewal, S. I. 2004. RITS acts in cis to promote RNA interference-mediated transcriptional and post-transcriptional silencing. Nat. Genet. 36, 11741180.
  • Partridge, J. F., Borgstrom, B. & Allshire, R. C. 2000. Distinct protein interaction domains and protein spreading in a complex centromere. Genes Dev. 14, 783791.
  • Partridge, J. F., Scott, K. S., Bannister, A. J., Kouzarides, T. & Allshire, R. C. 2002. cis-acting DNA from fission yeast centromeres mediates histone H3 methylation and recruitment of silencing factors and cohesin to an ectopic site. Curr. Biol. 12, 16521660.
  • Partridge, J. F., Debeauchamp, J. L., Kosinski, A. M., Ulrich, D. L., Hadler, M. J. & Noffsinger, V. J. 2007. Functional separation of the requirements for establishment and maintenance of centromeric heterochromatin. Mol. Cell 26, 593602.
  • Peters, A. H., O’carroll, D., Scherthan, H., Mechtler, K., Sauer, S., Schöfer, C., Weipoltshammer, K., Pagani, M., Lachner, M., Kohlmaier, A., Opravil, S., Doyle, M., Sibilia, M. & Jenuwein, T. 2001. Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability. Cell 107, 323337.
  • Pidoux, A. L. & Allshire, R. C. 2004. Kinetochore and heterochromatin domains of the fission yeast centromere. Chromosome Res. 12, 521534.
  • Rhind, N., Chen, Z., Yassour, M., Thompson, D. A., Haas, B. J., Habib, N., Wapinski, I., Roy, S., Lin, M. F., Heiman, D. I., Young, S. K., Furuya, K., Guo, Y., Pidoux, A., Chen, H. M., Robbertse, B., Goldberg, J. M., Aoki, K., Bayne, E. H., Berlin, A. M., Desjardins, C. A., Dobbs, E., Dukaj, L., Fan, L., Fitzgerald, M. G., French, C., Gujja, S., Hansen, K., Keifenheim, D., Levin, J. Z., Mosher, R. A., Müller, C. A., Pfiffner, J., Priest, M., Russ, C., Smialowska, A., Swoboda, P., Sykes, S. M., Vaughn, M., Vengrova, S., Yoder, R., Zeng, Q., Allshire, R., Baulcombe, D., Birren, B. W., Brown, W., Ekwall, K., Kellis, M., Leatherwood, J., Levin, H., Margalit, H., Martienssen, R., Nieduszynski, C. A., Spatafora, J. W., Friedman, N., Dalgaard, J. Z., Baumann, P., Niki, H., Regev, A. & Nusbaum, C. 2011. Comparative functional genomics of the fission yeasts. Science 332, 930936.
  • Sadaie, M., Iida, T., Urano, T. & Nakayama, J. 2004. A chromodomain protein, Chp1, is required for the establishment of heterochromatin in fission yeast. EMBO. J. 23, 38253835.
  • Sadaie, M., Kawaguchi, R., Ohtani, Y., Arisaka, F., Tanaka, K., Shirahige, K. & Nakayama, J. 2008. Balance between distinct HP1 family proteins controls heterochromatin assembly in fission yeast. Mol. Cell. Biol. 28, 69736988.
  • Schalch, T., Job, G., Noffsinger, V. J., Shanker, S., Kuscu, C., Joshua-Tor, L. & Partridge, J. F. 2009. High-affinity binding of Chp1 chromodomain to K9 methylated histone H3 is required to establish centromeric heterochromatin. Mol. Cell 34, 3646.
  • Schuettengruber, B. & Cavalli, G. 2009. Recruitment of polycomb group complexes and their role in the dynamic regulation of cell fate choice. Development 136, 35313542.
  • Scrima, A., Konickova, R., Czyzewski, B. K., Kawasaki, Y., Jeffrey, P. D., Groisman, R., Nakatani, Y., Iwai, S., Pavletich, N. P. & Thomä, N. H. 2008. Structural basis of UV DNA-damage recognition by the DDB1-DDB2 complex. Cell 135, 12131223.
  • Shanker, S., Job, G., George, O. L., Creamer, K. M., Shaban, A. & Partridge, J. F. 2010. Continuous requirement for the Clr4 complex but not RNAi for centromeric heterochromatin assembly in fission yeast harboring a disrupted RITS complex. PLoS Genet. 6, e1001174.
  • Sijen, T., Fleenor, J., Simmer, F., Thijssen, K. L., Parrish, S., Timmons, L., Plasterk, R. H. & Fire, A. 2001. On the role of RNA amplification in dsRNA-triggered gene silencing. Cell 107, 465476.
  • Smardon, A., Spoerke, J. M., Stacey, S. C., Klein, M. E., Mackin, N. & Maine, E. M. 2000. EGO-1 is related to RNA-directed RNA polymerase and functions in germ-line development and RNA interference in C. elegans. Curr. Biol. 10, 169178.
  • Song, J. J., Liu, J., Tolia, N. H., Schneiderman, J., Smith, S. K., Martienssen, R. A., Hannon, G. J. & Joshua-Tor, L. 2003. The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes. Nat. Struct. Biol. 10, 10261032.
  • Song, J. J., Smith, S. K., Hannon, G. J. & Joshua-Tor, L. 2004. Crystal structure of Argonaute and its implications for RISC slicer activity. Science 305, 14341437.
  • Takahashi, K., Murakami, S., Chikashige, Y., Funabiki, H., Niwa, O. & Yanagida, M. 1992. A low copy number central sequence with strict symmetry and unusual chromatin structure in fission yeast centromere. Mol. Biol. Cell 3, 819835.
  • Thon, G., Hansen, K. R., Altes, S. P., Sidhu, D., Singh, G., Verhein-Hansen, J., Bonaduce, M. J. & Klar, A. J. 2005. The Clr7 and Clr8 directionality factors and the Pcu4 cullin mediate heterochromatin formation in the fission yeast Schizosaccharomyces pombe. Genetics 171, 15831595.
  • Thon, G. & Verhein-Hansen, J. 2000. Four chromo-domain proteins of Schizosaccharomyces pombe differentially repress transcription at various chromosomal locations. Genetics 155, 551568.
  • Verdel, A., Jia, S., Gerber, S., Sugiyama, T., Gygi, S., Grewal, S. I. & Moazed, D. 2004. RNAi-mediated targeting of heterochromatin by the RITS complex. Science 303, 672676.
  • Volpe, T. A., Kidner, C., Hall, I. M., Teng, G., Grewal, S. I. & Martienssen, R. A. 2002. Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi. Science 297, 18331837.
  • Woolcock, K. J., Gaidatzis, D., Punga, T. & Buhler, M. 2011. Dicer associates with chromatin to repress genome activity in Schizosaccharomyces pombe. Nat. Struct. Mol. Biol. 18, 9499.
  • Wood, V., Gwilliam, R., Rajandream, M. A., Lyne, M., Lyne, R., Stewart, A., Sgouros, J., Peat, N., Hayles, J., Baker, S., Basham, D., Bowman, S., Brooks, K., Brown, D., Brown, S., Chillingworth, T., Churcher, C., Collins, M., Connor, R., Cronin, A., Davis, P., Feltwell, T., Fraser, A., Gentles, S., Goble, A., Hamlin, N., Harris, D., Hidalgo, J., Hodgson, G., Holroyd, S.Hornsby, T., Howarth, S., Huckle, E. J., Hunt, S., Jagels, K., James, K., Jones, L., Jones, M., Leather, S., McDonald, S., McLean, J., Mooney, P., Moule, S., Mungall, K., Murphy, L., Niblett, D., Odell, C., Oliver, K., O’Neil, S., Pearson, D., Quail, M. A., Rabbinowitsch, E., Rutherford, K., Rutter, S., Saunders, D., Seeger, K., Sharp, S., Skelton, J., Simmonds, M., Squares, R., Squares, S., Stevens, K., Taylor, K. & Taylor, R. G.Tivey, A., Walsh, S., Warren, T., Whitehead, S., Woodward, J., Volckaert, G., Aert, R., Robben, J., Grymonprez, B., Weltjens, I., Vanstreels, E., Rieger, M., Schäfer, M., Müller-Auer, S., Gabel, C., Fuchs, M., Düsterhöft, A., Fritzc, C., Holzer, E., Moestl, D., Hilbert, H., Borzym, K., Langer, I., Beck, A., Lehrach, H., Reinhardt, R., Pohl, T. M., Eger, P., Zimmermann, W., Wedler, H., Wambutt, R., Purnelle, B., Goffeau, A., Cadieu, E., Dréano, S., Gloux, S., Lelaure, V., Mottier, S. & Galibert, F.Aves, S. J., Xiang, Z., Hunt, C., Moore, K., Hurst, S. M., Lucas, M., Rochet, M., Gaillardin, C., Tallada, V. A., Garzon, A., Thode, G., Daga, R. R., Cruzado, L., Jimenez, J., Sánchez, M., del Rey, F., Benito, J., Domínguez, A., Revuelta, J. L., Moreno, S., Armstrong, J., Forsburg, S. L., Cerutti, L., Lowe, T., McCombie, W. R., Paulsen, I., Potashkin, J., Shpakovski, G. V., Ussery, D., Barrell, B. G. & Nurse, P. 2002. The genome sequence of Schizosaccharomyces pombe. Nature 415, 871880.
  • Zaratiegui, M., Castel, S., Irvine, D., Kloc, A., Ren, J., Li, F., de Castro, E., Marin, L., Antequera, F., Goto, D., Cande, Z., Arcangioli, B. & Martienssen, R. 2011. RNA interference promotes heterochromatic silencing through replication-coupled release of RNA polymerase II. Nature, doi: 10.1038/nature10501.
  • Zhang, K., Fischer, T., Porter, R. L., Dhakshnamoorthy, J., Zofall, M., Zhou, M., Veenstra, T. & Grewal, S. I. 2011. Clr4/Suv39 and RNA quality control factors cooperate to trigger RNAi and suppress antisense RNA. Science 331, 16241627.
  • Zofall, M., Fischer, T., Zhang, K., Zhou, M., Cui, B., Veenstra, T. D. & Grewal, S. I. 2009. Histone H2A.Z cooperates with RNAi and heterochromatin factors to suppress antisense RNAs. Nature 461, 419422.