Effect of drinking on the outcome of cirrhosis in patients with hepatitis B or C
Article first published online: 10 MAR 2008
Journal of Gastroenterology and Hepatology
Volume 7, Issue 3, pages 274–276, June 1992
How to Cite
SHIOMI, S., KUROKI, T., MINAMITANI, S., UEDA, T., NISHIGUCHI, S., NAKAJIMA, S., SEKI, S., KOBAYASHI, K. and HARIHARA, S. (1992), Effect of drinking on the outcome of cirrhosis in patients with hepatitis B or C. Journal of Gastroenterology and Hepatology, 7: 274–276. doi: 10.1111/j.1440-1746.1992.tb00979.x
- Issue published online: 10 MAR 2008
- Article first published online: 10 MAR 2008
- Accepted for publication 20 December 1991.
- hepatitis B virus;
- hepatitis C virus;
- survival rate.
Survival rates were calculated for 251 patients with cirrhosis of the liver but without hepatocellular carcinoma, primary biliary cirrhosis, or autoimmune cirrhosis who underwent laparoscopy during the past 21 years at the authors’ hospital. The survival rates were calculated by the Kaplan-Meier method. Stored serum was assayed for hepatitis B surface antigen (HBsAg) and antibodies to the hepatitis C virus (HCV). Patients with alcoholic cirrhosis had significantly better survival rates than patients with HBsAg, HCV, or both. Differences in survival rates between patients with hepatitis B and C were insignificant. In both groups, habitual drinkers had a significantly lower survival rate. The results suggested that alcohol accelerates liver damage in subjects with viral hepatitis.