Get access

Bacterial translocation: Overview of mechanisms and clinical impact

Authors

  • Silvio Balzan,

    1. Postgraduate Program, Gastroenterology Department, Digestive Surgery Division, University of Sao Paulo Medical School, Sao Paulo, Brazil.
    Search for more papers by this author
  • Claudio De Almeida Quadros,

    1. Postgraduate Program, Gastroenterology Department, Digestive Surgery Division, University of Sao Paulo Medical School, Sao Paulo, Brazil.
    Search for more papers by this author
  • Roberto De Cleva,

    1. Postgraduate Program, Gastroenterology Department, Digestive Surgery Division, University of Sao Paulo Medical School, Sao Paulo, Brazil.
    Search for more papers by this author
  • Bruno Zilberstein,

    1. Postgraduate Program, Gastroenterology Department, Digestive Surgery Division, University of Sao Paulo Medical School, Sao Paulo, Brazil.
    Search for more papers by this author
  • Ivan Cecconello

    1. Postgraduate Program, Gastroenterology Department, Digestive Surgery Division, University of Sao Paulo Medical School, Sao Paulo, Brazil.
    Search for more papers by this author

Dr Silvio Balzan, Rua General Vitorino, 330/1101, Porto Alegre, RS, Brazil. Email: sbalzan@hotmail.com

Abstract

Bacterial translocation (BT) is a phenomenon in which live bacteria or its products cross the intestinal barrier. Gut translocation of bacteria has been shown in both animal and human studies. BT and its complications have been shown clearly to occur in animal models, but its existence and importance in humans has been difficult to ascertain. We review the mechanisms of BT and its clinical impact based on the current literature.

Ancillary