P. N. Goldwater, FRACP, FRCPA, Senior Consultant Clinical Microbiologist.
Reappraisal of the SIDS enigma: An epidemiological and clinicopathological approach
Article first published online: 10 MAR 2008
Journal of Paediatrics and Child Health
Volume 28, Issue Supplement s1, pages S21–S25, August 1992
How to Cite
GOLDWATER, P. N. (1992), Reappraisal of the SIDS enigma: An epidemiological and clinicopathological approach. Journal of Paediatrics and Child Health, 28: S21–S25. doi: 10.1111/j.1440-1754.1992.tb02727.x
- Issue published online: 10 MAR 2008
- Article first published online: 10 MAR 2008
- Accepted for publication 18 February 1992.
- bacterial toxins;
- Escherichia colr;
- sudden infant death
Abstract The possibility that most cases of sudden infant death syndrome (SIDS) are caused by a transmissible agent is explored. A hypothesis of causation is developed using pathological and epidemiological data and our microbiological findings. The nature and distribution of vascular damage together with the consistent finding of liquid blood, in addition to the epidemiological features of SIDS, form the basis of the hypothesis that a bacterial toxin is a likely single cause of most cases of the syndrome. Future research ideas and a new definition of SIDS are proposed.