Fatal necrotizing pneumonia caused by group A streptococcus
Article first published online: 22 JAN 2004
Journal of Paediatrics and Child Health
Volume 40, Issue 1-2, pages 69–71, January 2004
How to Cite
Cengiz, A., Kanra, G., Cag^lar, M., Kara, A., Güçer, S. and İnce, T. (2004), Fatal necrotizing pneumonia caused by group A streptococcus. Journal of Paediatrics and Child Health, 40: 69–71. doi: 10.1111/j.1440-1754.2004.00296.x
- Issue published online: 22 JAN 2004
- Article first published online: 22 JAN 2004
- Accepted for publication 6 February 2003.
- group A streptococcus;
- invasive group A streptococcus infection;
Abstract: Group A streptococcus (GAS) causes invasive, non-invasive and non-suppurative diseases. Pneumonia is one of the invasive infections caused by GAS. Although GAS is a significant and serious cause of childhood pneumonia, it is often overlooked clinically. Similarly, the recent literature is surprisingly scant on reports of GAS pneumonia and concentrates mainly on varicella-associated invasive GAS diseases. In this case report, we present a previously healthy 7-year-old child with community-acquired pneumonia that progressed rapidly and resulted in sepsis, respiratory failure and death. In both blood and pleural fluid cultures, Streptococcus pyogenes were isolated. On autopsy, macroscopic examination revealed that the lung tissue appeared to have lost its normal architecture. Necrosis was present and the lung had a spongy appearance with some solid areas. The light microscopy revealed massive oedema, haemorrhages, intense inflammatory cell infiltration and necrosis. This case report highlights the need for consideration of invasive GAS infection in the event of severe, rapidly progressing pneumonia in children.