SEARCH

SEARCH BY CITATION

Keywords:

  • encephalopathy;
  • furosemide;
  • nephrotic syndrome;
  • respiratory failure

Abstract:  An 18-year-old girl with nephrotic syndrome presented with a life-threatening respiratory failure and a severe encephalopathy, shortly after being started on furosemide. The evaluation confirmed furosemide as the sole culprit for the clinical manifestations. This case highlights an unpredictable dose–response relationship of furosemide. The pathophysiological basis, differential diagnosis and clinical implications of the observed findings are discussed.