Funding: Asthma Foundation of Queensland and Royal Children's Hospital Foundation.
Asthma and protracted bronchitis: Who fares better during an acute respiratory infection?
Article first published online: 19 JAN 2009
© 2008 The Authors. Journal compilation © 2008 Paediatrics and Child Health Division (Royal Australasian College of Physicians)
Journal of Paediatrics and Child Health
Volume 45, Issue 1-2, pages 42–47, January/February 2009
How to Cite
Petsky, H. L., Acworth, J. P., Clark, R., Thearle, D. M., Masters, I. B. and Chang, A. B. (2009), Asthma and protracted bronchitis: Who fares better during an acute respiratory infection?. Journal of Paediatrics and Child Health, 45: 42–47. doi: 10.1111/j.1440-1754.2008.01433.x
- Issue published online: 19 JAN 2009
- Article first published online: 19 JAN 2009
- Accepted for publication 30 June 2008.
- respiratory tract infection
Aim: Acute respiratory infections (ARI) are common in children, and symptoms range from days to weeks. The aim of this study was to determine if children with asthma have more severe ARI episodes compared with children with protracted bronchitis and controls.
Methods: Parents prospectively scored their child's next ARI using the Canadian acute respiratory illness and flu scale (CARIFS) and a validated cough diary (on days 1–7, 10 and 14 of illness). Children were age- and season-matched.
Results: On days 10 and 14 of illness, children with protracted bronchitis had significantly higher median CARIFS when compared with children with asthma and healthy controls. On day 14, the median CARIFS were: asthma = 4.1 (interquartile range (IQR) 4.0), protracted bronchitis = 19.6 (IQR 25.8) and controls = 4.1 (IQR 5.25). The median cough score was significantly different between groups on days 1, 7, 10 and 14 (P < 0.001). A significantly higher proportion of children with protracted bronchitis (63%) were still coughing at day 14 in comparison with children with asthma (24%) and healthy controls (26%).
Conclusion: Children with protracted bronchitis had the most severe ARI symptoms and higher percentage of respiratory morbidity at day 14 in comparison with children with asthma and healthy controls.