Sterile abscess formation associated with depot leuprorelin acetate therapy for central precocious puberty
Article first published online: 12 MAY 2011
© 2011 The Authors. Journal of Paediatrics and Child Health © 2011 Paediatrics and Child Health Division (Royal Australasian College of Physicians)
Journal of Paediatrics and Child Health
Volume 48, Issue 3, pages E136–E139, March 2012
How to Cite
Johnson, S. R., Nolan, R. C., Grant, M. T., Price, G. J., Siafarikas, A., Bint, L. and Choong, C. S. (2012), Sterile abscess formation associated with depot leuprorelin acetate therapy for central precocious puberty. Journal of Paediatrics and Child Health, 48: E136–E139. doi: 10.1111/j.1440-1754.2011.02083.x
- Issue published online: 14 MAR 2012
- Article first published online: 12 MAY 2011
- Accepted for publication 23 December 2010.
- GnRH analogue;
- precocious puberty;
- sterile abscess
We describe a case of an 8 year old girl with central precocious puberty. She was commenced on 3 monthly intramuscular depot Leuprorelin acetate therapy, as a result of which she developed sterile abscesses. She was converted to daily subcutaneous Leuprorelin acetate therapy with no recurrence of the abscesses. The possible mechanisms for this reaction are described in the article.