Clinical variables at age 2 predictive of mental retardation at age 5 in children with pervasive developmental disorder
Article first published online: 1 DEC 2005
Psychiatry and Clinical Neurosciences
Volume 59, Issue 6, pages 717–722, December 2005
How to Cite
TAKEDA, T., KOYAMA, T., KANAI, C. and KURITA, H. (2005), Clinical variables at age 2 predictive of mental retardation at age 5 in children with pervasive developmental disorder. Psychiatry and Clinical Neurosciences, 59: 717–722. doi: 10.1111/j.1440-1819.2005.01442.x
- Issue published online: 1 DEC 2005
- Article first published online: 1 DEC 2005
- Received 4 March 2005; revised 30 May 2005; accepted 12 June 2005.
- autistic disorder;
- mental retardation;
- pervasive developmental disorder;
Abstract This study attempted to find clinical variables evaluated at age 2 that would predict mental retardation (MR, IQ/cognition-adaptation developmental quotient [C-A DQ] < 70) at age 5 in 57 children with pervasive developmental disorder (PDD). About two-thirds of subjects had MR at both initial and outcome evaluations. The C-A DQ at initial evaluation was significantly lower in mentally retarded PDD (MRPDD) than in high-functioning (IQ ≥ 70) PDD (HFPDD). MRPDD changed less than HFPDD in IQ/C-A DQ between ages 2 and 5. The C-A DQ at age 2 was a potent predictor for MR at age 5 and the total score and three item scores of Childhood Autism Rating Scale-Tokyo Version evaluated at age 2 were also useful in predicting MR at age 5.