Effectiveness of kamishoyosan for premenstrual dysphoric disorder: Open-labeled pilot study
Article first published online: 28 APR 2007
Psychiatry and Clinical Neurosciences
Volume 61, Issue 3, pages 323–325, June 2007
How to Cite
YAMADA, K. and KANBA, S. (2007), Effectiveness of kamishoyosan for premenstrual dysphoric disorder: Open-labeled pilot study. Psychiatry and Clinical Neurosciences, 61: 323–325. doi: 10.1111/j.1440-1819.2007.01649.x
- Issue published online: 28 APR 2007
- Article first published online: 28 APR 2007
- Received 4 April 2006; revised 22 December 2006; accepted 6 January 2007.
- alternative treatment;
- premenstrual dysphoric disorder
Abstract The purpose of the present paper was to investigate the efficacy of kamishoyosan (TJ-24), a traditional Japanese herbal formula (kampo), for outpatients with premenstrual dysphoric disorder (PMDD) as an alternative treatment. Thirty patients with PMDD were treated with TJ-24 for six menstrual cycles. Nineteen patients (63.3%) had >50% improvement in the total score of the Hamilton Depression Rating Scale (HAM-D) Scale (17 items) in the late luteal phase. Fourteen patients (46.7%) went into remission (total HAM-D score <7). In the present study many patients with PMDD were successfully treated with TJ-24.