Relationship of psychopathological symptoms and cognitive function to subjective quality of life in patients with chronic schizophrenia
Article first published online: 24 NOV 2009
© 2009 The Authors. Journal compilation © 2009 Japanese Society of Psychiatry and Neurology
Psychiatry and Clinical Neurosciences
Volume 64, Issue 1, pages 62–69, February 2010
How to Cite
Tomida, K., Takahashi, N., Saito, S., Maeno, N., Iwamoto, K., Yoshida, K., Kimura, H., Iidaka, T. and Ozaki, N. (2010), Relationship of psychopathological symptoms and cognitive function to subjective quality of life in patients with chronic schizophrenia. Psychiatry and Clinical Neurosciences, 64: 62–69. doi: 10.1111/j.1440-1819.2009.02033.x
- Issue published online: 20 JAN 2010
- Article first published online: 24 NOV 2009
- Received 24 March 2009; revised 27 August 2009; accepted 9 September 2009.
- positive and negative syndrome scale;
- quality of life;
- regression analysis;
Aims: The purpose of the present study was to examine the extent of the effects of psychopathological symptoms and cognitive function on quality of life (QOL) in patients with chronic schizophrenia.
Methods: Data were obtained using the Japanese Schizophrenia Quality of Life Scale (JSQLS), Positive and Negative Syndrome Scale (PANSS), Wisconsin Card-Sorting Test (WCST) Keio version, and Continuous Performance Test (CPT) for 52 schizophrenia patients.
Results: Stepwise regression analysis showed that PANSS depression/anxiety factors predicted JSQLS psychosocial conditions and motivation/energy, and that WCST Categories Achieved predicted JSQLS symptoms/side-effects.
Conclusions: Psychopathological symptoms and cognitive function affect subjective QOL in patients with schizophrenia. If the final goal is treatment that improves QOL in a manner that patients themselves are aware of, clinicians probably need to consider a treatment strategy that improves depression/anxiety symptom.