Fronto-limbic abnormalities in a patient with compulsive hoarding: a 99mTc-ECD SPECT study
Article first published online: 19 AUG 2010
© 2010 The Authors. Journal compilation © 2010 Japanese Society of Psychiatry and Neurology
Psychiatry and Clinical Neurosciences
Volume 64, Issue 5, pages 580–583, October 2010
How to Cite
Ohtsuchi, H., Matsuo, K., Akimoto, T. and Watanabe, Y. (2010), Fronto-limbic abnormalities in a patient with compulsive hoarding: a 99mTc-ECD SPECT study. Psychiatry and Clinical Neurosciences, 64: 580–583. doi: 10.1111/j.1440-1819.2010.02120.x
- Issue published online: 28 SEP 2010
- Article first published online: 19 AUG 2010
- Received 14 December 2009; revised 14 June 2010; accepted 18 June 2010.
- gyrus cinguli;
- obsessive-compulsive disorder;
- single-photon emission
Little is known about the neuronal mechanism underpinning the pathophysiology of compulsive hoarding. We report the cerebral blood flow changes in an obsessive-convulsive patient with severe hoarding. The patient showed hyperperfusion of the fronto-temporal region and hypoperfusion of the striatal, the middle cingulate and the medial temporal regions during the stage with severe symptoms. Following improvement from the hoarding behaviors, the extent of hypoperfusion was expanded in the bilateral striatum, the anterior and middle cingulate gyrus. The result may substantiate evidence of the fronto-limbic abnormality involved in the pathophysiology of compulsive hoarding.