• 1
    Isomaa B, Almgren P, Tuomi T et al. Cardiovascular morbidity and mortality associated with the metabolic syndrome. Diabetes Care 2001; 24: 683689.
  • 2
    Lakka HM, Laaksonen DE, LakkaTA et al. The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men. JAMA 2002; 288: 27092716.
  • 3
    Ford ES, Giles WH, Dietz WH. Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey. JAMA 2002; 287: 356359.
  • 4
    Meigs JB, Wilson PWF, Fox CS et al. Body mass index, metabolic syndrome, and risk of type 2 diabetes or cardiovascular disease. J. Clin. Endocrinol. Metab. 2006; 91: 29062912.
  • 5
    Kurl S, Laukkanen JA, Niskanen L et al. Metabolic syndrome and the risk of stroke in middle-aged men. Stroke 2006; 37: 806811.
  • 6
    Ford ES, Giles WH, Mokdad AH. Increasing prevalence of the metabolic syndrome among U.S. adults. Diabetes Care 2004; 27: 24442449.
  • 7
    Balkau B, Vernay M, Mhamdi L et al. The incidence and persistence of the NCEP (National Cholesterol Education Program) metabolic syndrome. The French D.E.S.I.R. study. Diabetes Metab. 2003; 29: 526532.
  • 8
    Hu G, Qiao Q, Tuomilehto J, Balkau B, Borch-Johnsen K, Pyorala K. Prevalence of the metabolic syndrome and its relation to all-cause and cardiovascular mortality in nondiabetic European men and women. Arch. Intern. Med. 2004; 164: 10661076.
  • 9
    Miccoli R et al. Prevalence of the metabolic syndrome among Italian adults according to ATP III definition. Nutr. Metab. Cardiovasc. Dis. 2005; 15: 250254.
  • 10
    Perez Jimenez F, Mora Navarro G, Diez Espino J. Impacto del síndrome metabolico en la salud publica en España. Med. Clin. (Barc) 2006; 7: 812.
  • 11
    Cameron AJ, Shaw JE, Zimmet PZ. The metabolic syndrome: prevalence in worldwide populations. Endocrinol. Metab. Clin. North. Am. 2004; 33: 351375.
  • 12
    Eckel RH, Grundy SM, Zimmet PZ. The metabolic syndrome. Lancet 2005; 365: 14151428.
  • 13
    Fiedorowicz JG, Palagummi NM, Forman-Hoffman VL, Miller DD, Haynes WG. Elevated prevalence of obesity, metabolic syndrome, and cardiovascular risk factors in bipolar disorder. Ann. Clin. Psychiatry 2008; 20: 131137.
  • 14
    Fagiolini A, Frank E, Turkin S, Houck PR, Soreca I, Kupfer DJ. Metabolic syndrome in patients with bipolar disorder. J. Clin. Psychiatry 2008; 69: 678679.
  • 15
    Cardenas J, Frye MA, Marusak SL et al. Modal subcomponents of metabolic syndrome in patients with bipolar disorder. J. Affect. Disord. 2008; 106: 9197.
  • 16
    van Winkel R, De Hert M, Van Eyck D et al. Prevalence of diabetes and the metabolic syndrome in a sample of patients with bipolar disorder. Bipolar Disord. 2008; 10: 342348.
  • 17
    Salvi V, Albert U, Chiarle A, Soreca I, Bogetto F, Maina G. Metabolic syndrome in Italian patients with bipolar disorder. Gen. Hosp. Psychiatry 2008; 30: 318323.
  • 18
    Murray DP, Weiner M, Prabhakar M, Fiedorowicz JG. Mania and mortality: why the excess cardiovascular risk in bipolar disorder? Curr. Psychiatry Rep. 2009; 11: 475480.
  • 19
    First MB, Spitzer RL, Gibbon M, Williams JBW. Structured Clinical Interview for the Diagnostic and Statistical Manual, 4th edn. American Psychiatric Press, Washington, DC, Patient Version, 1997.
  • 20
    Bo S, Ciccone G, Pearce N et al. Prevalence of undiagnosed metabolic syndrome in a population of adult asymptomatic subjects. Diabetes Res. Clin. Pract. 2007; 75: 362365.
  • 21
    World Health Organization. Obesity: Preventing and Managing the Global Epidemic: Report of A WHO Consultation on Obesity. World Health Organisation, Geneva, 1997.
  • 22
    James WP. The dietary challenge for the European Union. Public Health Nutr. 2001; 4: 341351.
  • 23
    Grundy SM, Cleeman JI, Daniels SR et al. American Heart Association, National Heart, Lung, and Blood Institute. Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Circulation 2005; 112: 27352752.
  • 24
    Bonora E, Kiechl S, Willeit J et al. Bruneck Study. Metabolic syndrome: epidemiology and more extensive phenotypic description. Cross-sectional data from the Bruneck Study. Int. J. Obes. Relat. Metab. Disord. 2003; 27: 12831289.
  • 25
    Scott KM, Bruffaerts R, Simon GE et al. Obesity and mental disorders in the general population: results from the world mental health surveys. Int. J. Obes. (Lond) 2008; 32: 192200.
  • 26
    Garcia-Portilla MP, Saiz PA, Benabarre A et al. The prevalence of metabolic syndrome in patients with bipolar disorder. J. Affect. Disord. 2008; 106: 197201.
  • 27
    Sicras A, Rejas J, Navarro R, Serrat J, Blanca M. Metabolic syndrome in bipolar disorder: a cross-sectional assessment of a Health Management Organization database. Bipolar Disord. 2008; 10: 607616.
  • 28
    Kuzuya M, Ando F, Iguchi A, Shimokata H. Age-specific change of prevalence of metabolic syndrome: longitudinal observation of large Japanese cohort. Atherosclerosis 2007; 191: 305312.
  • 29
    Henderson DC. Diabetes mellitus and other metabolic disturbances induced by atypical antipsychotic agents. Curr. Diab. Rep. 2002; 2: 135140.
  • 30
    Yumru M, Savas HA, Kurt E et al. Atypical antipsychotics related metabolic syndrome in bipolar patients. J. Affect. Disord. 2007; 98: 247252.
  • 31
    Taylor V, MacQueen G. Associations between bipolar disorder and metabolic syndrome: a review. J. Clin. Psychiatry 2006; 67: 10341041.
  • 32
    Maina G, Salvi V, Vitalucci A, D'Ambrosio V, Bogetto F. Prevalence and correlates of overweight in drug-naïve patients with bipolar disorder. J. Affect. Disord. 2008; 110: 149155.
  • 33
    Achten J, Jeukendrup AE. Optimizing fat oxidation through exercise and diet. Nutrition 2004; 20: 716727.
  • 34
    Solomon TP, Krishnan RK, Del Aguila LF et al. Exercise and diet enhance fat oxidation and reduce insulin resistance in older obese adults. J. Appl. Physiol. 2008; 104: 13131319.
  • 35
    Fleet-Michaliszyn SB, Soreca I, Otto AD et al. A prospective observational study of obesity, body composition, and insulin resistance in 18 women with bipolar disorder and 17 matched control subjects. J. Clin. Psychiatry 2008; 69: 18921900.
  • 36
    van Winkel R, van Os J, Celic I et al. Psychiatric diagnosis as an independent risk factor for metabolic disturbances: results from a comprehensive, naturalistic screening program. J. Clin. Psychiatry 2008; 69: 13191327.