Cerebral blood flow changes in very-late-onset schizophrenia-like psychosis with catatonia before and after successful treatment
Article first published online: 17 OCT 2011
© 2011 The Authors. Psychiatry and Clinical Neurosciences © 2011 Japanese Society of Psychiatry and Neurology
Psychiatry and Clinical Neurosciences
Volume 65, Issue 6, pages 600–603, October 2011
How to Cite
Tsujino, N., Nemoto, T., Yamaguchi, T., Katagiri, N., Tohgi, N., Ikeda, R., Shiraga, N., Mizumura, S. and Mizuno, M. (2011), Cerebral blood flow changes in very-late-onset schizophrenia-like psychosis with catatonia before and after successful treatment. Psychiatry and Clinical Neurosciences, 65: 600–603. doi: 10.1111/j.1440-1819.2011.02257.x
- Issue published online: 17 OCT 2011
- Article first published online: 17 OCT 2011
- Received 17 December 2010; revised 7 July 2011; accepted 18 July 2011.
- easy Z-score imaging system;
- very-late-onset schizophrenia-like psychosis
The purpose of the present study was to investigate regional cerebral blood flow (rCBF) changes in a patient with very-late-onset schizophrenia-like psychosis (VLOS) with catatonia. A 64-year-old woman developed catatonia after experiencing persecutory delusions. The patient's rCBF was examined using single photon emission computed tomography (SPECT) with easy Z-score imaging system. Before treatment, hypoperfusion was observed in the striatum and the thalamus, whereas hyperperfusion was observed in the left lateral frontal cortex and the left temporal cortex. After treatment, the disproportions in rCBF disappeared, and hyperperfusion was observed in the motor cortex. Sequential SPECT findings suggest that rCBF abnormalities may be correlated with the symptomatology of catatonia in patients with VLOS.