Insight in schizophrenia: From conceptualization to neuroscience
Article first published online: 23 MAR 2012
© 2012 The Authors. Psychiatry and Clinical Neurosciences © 2012 Japanese Society of Psychiatry and Neurology
Psychiatry and Clinical Neurosciences
Volume 66, Issue 3, pages 167–179, April 2012
How to Cite
Ouzir, M., Azorin, J. M., Adida, M., Boussaoud, D. and Battas, O. (2012), Insight in schizophrenia: From conceptualization to neuroscience. Psychiatry and Clinical Neurosciences, 66: 167–179. doi: 10.1111/j.1440-1819.2012.02325.x
- Issue published online: 23 MAR 2012
- Article first published online: 23 MAR 2012
- Received 3 October 2010; accepted 25 January 2012.
- cognition impairment;
Lack of insight into illness is a prevalent and distinguishing feature of schizophrenia, which has a complex history and has been given a variety of definitions. Currently, insight is measured and treated as a multidimensional phenomenon, because it is believed to result from psychological, neuropsychological and organic factors. Thus, schizophrenia patients may display dramatic disorders including demoralization, depression and a higher risk of suicide, all of which are directly or indirectly related to a lack of insight into their illness, and make the treatment difficult. To improve the treatment of people with schizophrenia, it is thus crucial to advance research on insight into their illness. Insight is studied in a variety of ways. Studies may focus on the relationship between insight and psychopathology, may view behavioral outcomes or look discretely at the cognitive dysfunction versus anatomy level of insight. All have merit but they are dispersed across a wide body of literature and rarely are the findings integrated and synthesized in a meaningful way. The aim of this study was to synthesize findings across the large body of literature dealing with insight, to highlight its multidimensional nature, measurement, neuropsychology and social impact in schizophrenia. The extensive literature on the cognitive consequences of lack of insight and the contribution of neuroimaging techniques to elucidating neurological etiology of insight deficits, is also reviewed.