Adult teratoid Wilms' tumor with prominent neuroepithelial differentiation
Article first published online: 15 DEC 2008
© 2009 The Authors. Journal compilation © 2009 Japanese Society of Pathology
Volume 59, Issue 1, pages 44–48, January 2009
How to Cite
Seo, J., Suh, Y.-L. and Choi, H. Y. (2009), Adult teratoid Wilms' tumor with prominent neuroepithelial differentiation. Pathology International, 59: 44–48. doi: 10.1111/j.1440-1827.2008.02323.x
- Issue published online: 15 DEC 2008
- Article first published online: 15 DEC 2008
- Received 23 April 2008. Accepted for publication 20 August 2008.
- neuroepithelial tissue;
- teratoid Wilms' tumor
Teratoid Wilms' tumor is a rare variant of Wilms' tumor (WT) that has been reported exclusively in pediatric patients. The present paper describes a teratoid WT in a 50-year-old Korean man with a giant right renal mass. Radical nephrectomy was performed under the impression that the mass was a renal cell carcinoma. Grossly, the removed kidney contained a giant well-encapsulated mass measuring 24 × 18 × 10 cm with cystic changes, necrosis, and hemorrhage. On microscopy triphasic patterns of WT and prominent heterologous components were seen, including rhabdomyoblasts, neuroepithelial tissue, fat, cartilage, and various types of mature epithelium. This is the first reported case of a teratoid WT occurring in an adult kidney.