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Strategies for non-responders
Article first published online: 19 OCT 2009
DOI: 10.1111/j.1440-1843.2009.01575.x
© 2009 The Japanese Respiratory Society. Journal compilation © 2009 Asian Pacific Society of Respirology
Issue
Respirology
Special Issue: The Japanese Respiratory Society Guidelines for the Management of Hospital-Acquired Pneumonia in Adults
Volume 14, Issue Supplement s2, pages S41–S43, November 2009
Additional Information
How to Cite
(2009), Strategies for non-responders. Respirology, 14: S41–S43. doi: 10.1111/j.1440-1843.2009.01575.x
Publication History
- Issue published online: 19 OCT 2009
- Article first published online: 19 OCT 2009
- Abstract
- Article
- References
- Cited By
SUMMARY
• When improvements in symptoms of hospital-acquired pneumonia are difficult to see, an investigation should be made into whether there truly is no response to antimicrobial treatment.
• Non-infectious disease that results in pneumonia-like shadows needs to be excluded.
• In pneumonia that is unresponsive to antimicrobials, differential diagnoses must be made with consideration of causative microorganism factors, host factors and medication factors, respectively.
• Preferably, the dose, administration frequency and administration time for the administered antimicrobials should be established based on PK/PD.